Optimisation of peptidic non-phosphorylated inhibitors of the Grb7 SH2 domain

Grb7 SH2 结构域肽类非磷酸化抑制剂的优化

• 批准号: DP0987761
• 负责人: Prof Jacqueline Wilce
• 金额: $ 29.1万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-05 至 2011-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0987761
• 关键词: Optimisation; peptidic; non; phosphorylated; inhibitors

The research outcomes will be of fundamental importance in the field of inhibitor development and as such will result in publications in high-profile international journals and continue to contribute to Australia's outstanding international reputation in biological research. Students and research associates that have the opportunity to work on this project will be trained in the use of state-of-the art technologies in biochemistry, scientific rigour and presentation skills and thus contribute to the quality of our national workforce. Furthermore, applications that arise from this work will contribute to Australia's intellectual property and future developments in the pharmaceutical industry.

研究成果将在抑制剂开发领域具有根本性的重要性，因此将在知名国际期刊上发表文章，并继续为澳大利亚在生物研究领域的杰出国际声誉做出贡献。有机会参与这一项目的学生和研究人员将接受在生物化学、科学严谨性和陈述技能方面使用最先进技术的培训，从而提高我们国家劳动力的质量。此外，这项工作产生的申请将有助于澳大利亚的知识产权和制药业的未来发展。