Analyzing Major Sources of Variation in the Relation Between Metabolic Heat Production and Respiratory Gas Exchange

分析代谢产热与呼吸气体交换之间关系变化的主要来源

• 批准号: 0210804
• 负责人: Glenn Walsberg
• 金额: $ 31.5万
• 依托单位: Arizona State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0210804&HistoricalAwards=false
• 关键词: Analyzing; Major; Sources; Variation; Relation

Energy is vital for both the propagation and maintenance of organisms. Thus, the use of metabolic energy and the heat that is produced as its byproduct is a major theme in modern biology. Animal energy usage is usually measured by "indirect calorimetry" that relies upon the exchange of respiratory gases by the organism (e.g., oxygen consumption or carbon dioxide production). An important complication in such analyses is that the relationship between respiratory gas exchange at the lungs and metabolic heat production is variable. These variations could have important consequences for our understanding of energy use by animals by producing substantial (e.g., 30%) errors in energetic analyses. This project will quantify the relationships between metabolic heat production in animals and their respiratory gas exchange, and determine the sensitivity of these relations to variables most likely to importantly affect energy metabolism. Critical variables to be explored include diet composition, intensity of metabolism, time of day relative to the animal's physiological cycles, and extent of time spent feeding or fasting. The most likely physiological bases of currently unexplainable variation in the relations between respiratory gas exchange and metabolic heat production will be explored. This portion of the research will focus on quantifying the various fates of the carbon dioxide that is produced by animal metabolism (e.g., exhaled through the lungs, stored in the body). This research will be conducted using a broad range of animals (insects, reptiles, birds) in order to evaluate the extent of biological variation in these basic energy relations.

能量对于生物体的繁殖和维持都是至关重要的。因此，利用代谢能及其副产品产生的热量是现代生物学的一个主要主题。 动物能量使用通常通过依赖于生物体呼吸气体交换的“间接量热法”来测量（例如，氧气消耗或二氧化碳产生）。 这种分析的一个重要的复杂性是，在肺部的呼吸气体交换和代谢产热之间的关系是可变的。 这些变化可能对我们理解动物通过产生大量的能量（例如，30%）的能量分析误差。 该项目将量化动物代谢产热与呼吸气体交换之间的关系，并确定这些关系对最有可能影响能量代谢的变量的敏感性。 要探索的关键变量包括饮食组成，代谢强度，一天中相对于动物生理周期的时间，以及进食或禁食的时间范围。 目前无法解释的呼吸气体交换和代谢产热之间的关系的变化最可能的生理基础将进行探讨。 这部分研究将侧重于量化动物代谢产生的二氧化碳的各种命运（例如，通过肺部呼出，储存在体内）。 这项研究将使用广泛的动物（昆虫，爬行动物，鸟类）进行，以评估这些基本能量关系的生物变异程度。