Development of a 2D Vibrational Spectrometer for Materials Characterization Based on NMR Analogs

开发基于 NMR 类似物的材料表征二维振动光谱仪

• 批准号: 0216056
• 负责人: Mark Berg
• 金额: $ 50.07万
• 依托单位: University South Carolina Research Foundation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0216056&HistoricalAwards=false
• 关键词: Development; 2D; Vibrational; Spectrometer; Materials

With support from the Major Research Instrumentation (MRI) and Chemistry Research Instrumentation and Facilities (CRIF) Programs, Prof. Mark A. Berg of the University of South Carolina will develop a state-of-the-art 2D vibrational spectrometer for materials characterization based on NMR analogs. Two-dimensional vibrational spectroscopy can be used to directly probe the inter- and intramolecular vibrational coupling patterns in complex molecular systems. The 2D vibrational spectrometer combining infrared and Raman lasers can be used to study time-resolved structural evolutions of various systems including protein-ligand, organic-inorganic materials and other systems. Thus it promises to be one of the major experimental tools in characterizing the molecular nature of functional materials such as conjugated polyenes, in determining ultrafast dynamics of protein and protein-ligand binding processes, and in studying microscopic solvation dynamics by directly probing the real-time dynamics of solvent molecules close to solute molecules. These studies will have important consequences in each of the above areas, and accelerate the national development of two dimensional vibrational spectroscopy, an important emerging area. In addition, student participants will be exposed to a wide range of techniques.

在主要研究仪器（MRI）和化学研究仪器和设施（CRIF）计划的支持下，Mark A.南卡罗来纳州大学的贝格将开发一种最先进的二维振动光谱仪，用于基于NMR类似物的材料表征。 二维振动光谱可以用来直接探测复杂分子体系中分子间和分子内的振动耦合模式。 红外和拉曼激光相结合的二维振动光谱仪可用于研究蛋白质-配体、有机-无机材料等体系的时间分辨结构演化。 因此，它有望成为一个主要的实验工具，在表征功能材料，如共轭多烯的分子性质，在确定蛋白质和蛋白质-配体结合过程的超快动力学，并在研究微观溶剂化动力学直接探测接近溶质分子的溶剂分子的实时动力学。 这些研究将在上述每个领域产生重要影响，并加速国家发展二维振动光谱学，这是一个重要的新兴领域。 此外，学生参与者将接触到广泛的技术。