RUI: MRI: Acquisition of Fluorescence Microscopy Instrumentation for Research and Education in Biology, Geology, and Neuroscience

NSF 2002年5月2日电子邮件中要求的项目：NSF或任何其他机构都没有审查本提案或类似提案。NSF-MRI摘要：Colgate大学的Ken Belanger博士获得了一笔赠款，用于开发用于研究和本科教育的荧光显微镜设备。该合同将允许购买四台荧光显微镜和随附的高分辨率数码相机，以及一个可变温度的舞台安装孵化室。该仪器将用于高露洁大学和汉密尔顿学院的生物学、地质学和神经科学系的教师和学生研究项目以及调查性教学实验室练习。该提案资助的荧光显微镜设施最初将支持6个研究项目和7个本科生实验室课程，并将提供给未包括在原始提案中的教师和实验室课程使用。该提案中概述的研究项目涉及各种学科的广泛问题，包括细胞内蛋白质靶向的检查（Belanger，项目1），南极古地质学（Leventer，项目2），多巴胺诱导的神经调节（Tierney，项目3），极端温度下的基因表达（Hoopes，项目4）、神经传递的类固醇激素调节（Lehman，项目5）和细胞内信号传递（Festin，项目6）。此外，显微镜设施将用于七个不同的实验室课程（项目7）的教育目的，包括细胞生物学，环境研究，遗传学，分子分析，神经生理学和发育生物学。根据目前的研究活动和课程报名情况，每年约有30名独立研究生和180 - 200名实验室课程参与者将使用该显微镜设施。因此，该设施不仅有助于提高该联盟内进行的研究质量，而且还将提高大量本科生的教育经验，技术准备和继续科学研究的热情。

Items requested in NSF email of 5/2/02:Neither this proposal nor a similar one is under review at NSF or any other agency. NSF-MRI Abstract:A grant has been awarded to Dr. Ken Belanger at Colgate University for the development of a fluorescence light microscopy facility to be used for research and undergraduate education. This award will allow the acquisition of four fluorescence light microscopes and accompanying high-resolution digital cameras, as well as a variable temperature, stage-mounted incubation chamber. This instrumentation will be used for faculty and student research projects as well as investigative teaching laboratory exercises in the Biology, Geology, and Neuroscience Departments at both Colgate University and Hamilton College.The fluorescence microscopy facility funded by this proposal will initially support six research projects and seven undergraduate laboratory courses, and will be available for use by faculty members and laboratory courses not included in the original proposal. The research projects outlined in this proposal address a broad range of questions across a variety of disciplines, including examination of intracellular protein targeting (Belanger, project 1), Antarctic paleogeology (Leventer, project 2), dopamine-induced neuromodulation (Tierney, project 3), gene expression at temperature extremes (Hoopes, project 4), steroid hormone regulation of neurotransmission (Lehman, project 5), and intracellular signal transmission (Festin, project 6). In addition, the microscopy facility will be used for educational purposes for seven different laboratory courses (project 7), including Cell Biology, Environmental Studies, Genetics, Molecular Analysis, Neurophysiology, and Developmental Biology. Based on current research activities and course enrollments, approximately 30 independent research students and 180 - 200 lab course participants will utilize this microscopy facility annually. Thus, this facility will not only serve to enhance the quality of research performed within this consortium, but will also enhance the educational experience, technological preparedness, and enthusiasm for continued scientific research for a significant number of undergraduate students.