Purchase of an 'Exact Mass' Spectrometry System

购买“精确质谱”光谱系统

• 批准号: 0234501
• 负责人: David Coleman
• 金额: $ 16.88万
• 依托单位: Wayne State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-03-15 至 2006-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0234501&HistoricalAwards=false
• 关键词: Purchase; Exact; Mass; Spectrometry; System

With support from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at Wayne State University will purchase a Mass Spectrometer. This equipment will enhance research in a number of areas including 1) the development of new nickel-catalyzed reactions and the total synthesis of complex natural products; 2) the development of new metathesis-based approaches to C-glycosides; 3) the total synthesis of pharmacologically active natural products; 4) synthesis of complex carbohydrates and natural products; 5) synthesis of natural products through biosynthetic pathway engineering; and 6) the design and synthesis of enzyme and receptor inhibitors. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. It is one of the fastest growing and most widely used analytical instrumentation techniques. Because of this, it is important for undergraduate and graduate students to be exposed to the technique. Graduate students, undergraduate summer and postdocs will use this instrument for their research.

在化学研究仪器和设施（CRIF）计划的支持下，韦恩州立大学化学系将购买一台质谱仪。该设备将加强若干领域的研究，包括：（1）开发新的镍催化反应和复杂天然产物的全合成;（2）开发新的基于复分解的C-糖苷方法;（3）全合成具有生物活性的天然产物;（4）合成复杂碳水化合物和天然产物; 5）通过生物合成途径工程合成天然产物;和6）酶和受体抑制剂的设计和合成。质谱（MS）是一种用于探测紧密结构细节并获得大量有机、生物有机和有机金属分子的分子组成的技术。 它是发展最快、使用最广泛的分析仪器技术之一。 因此，本科生和研究生接触这项技术是很重要的。 研究生，本科生暑期和博士后将使用此仪器进行研究。