CAREER: Polynuclear Lanthanide-Oxo/Hydroxo Clusters - Design, Preparation, and Applications

职业：多核镧系元素-氧/羟基团簇 - 设计、制备和应用

• 批准号: 0238790
• 负责人: Zhiping Zheng
• 金额: $ 48万
• 依托单位: University of Arizona
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0238790&HistoricalAwards=false
• 关键词: CAREER; Polynuclear; Lanthanide; Oxo; Hydroxo

This CAREER award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports research by Professor Zhiping Zheng at the University of Arizona to design and synthesize a novel class of polynuclear lanthanide complexes, to study the properties of these substances, and to explore their biomedical and advanced technological applications.The primary goal is to develop a fundamental understanding of lanthanide coordination chemistry under physiological or higher pH conditions with a variety of ligands, including those that are biologically relevant. These efforts are aimed at producing a variety of unprecedented lanthanide clusters featuring highly bridging oxo and hydroxo groups and at elucidating the factors governing the formation of these novel substances. The potential applications to be explored include contrast agents for biomedical imaging, luminescent materials for liquid crystal displays, and magnetooptical data storage. The broad scope and modular nature of the work involves cross-disciplinary collaborations and provides diverse opportunities for training of students at all levels. In line with the proposed research, educational activities are proposed aimed at establishing a well-defined program in Materials Chemistry integrated into the undergraduate or graduate curricula at the University of Arizona. The ultimate goal is to produce scientists who are capable of designing, synthesizing, characterizing, and testing new materials to meet the challenging demand for advanced-performance materials in the next century. This educational program will also serve as a vehicle to disseminate chemical science to the general public.

该无机、生物无机和有机金属化学项目的职业奖支持亚利桑那大学郑志平教授的研究，旨在设计和合成一类新型多核稀土配合物，研究这些物质的性质，并探索它们的生物医学和先进技术应用。主要目标是在生理或更高水平下对稀土配位化学有一个基本的了解。 具有多种配体的 pH 条件，包括那些与生物学相关的配体。 这些努力旨在产生各种前所未有的具有高度桥接的氧代和羟基基团的镧系元素簇，并阐明控制这些新物质形成的因素。 待探索的潜在应用包括用于生物医学成像的造影剂、用于液晶显示器的发光材料和磁光数据存储。 这项工作的广泛范围和模块化性质涉及跨学科合作，并为各级学生的培训提供了多样化的机会。 根据拟议的研究，建议开展教育活动，旨在建立一个明确的材料化学课程，并将其纳入亚利桑那大学的本科或研究生课程。 最终目标是培养能够设计、合成、表征和测试新材料的科学家，以满足下世纪对先进性能材料的挑战性需求。 该教育计划还将作为向公众传播化学科学的工具。