Intermolecular and Intramolecular Electron Transfer Reactions

有了这个更新建议的有机和高分子化学计划支持教授斯蒂芬尼尔森在化学系在威斯康星州-麦迪逊大学正在进行的工作。Nelsen教授的这项工作概述了各种桥接供体-受体化合物（主要是双肼）中电子转移的几种机理研究。Nelsen教授试图继续他的工作，在分子内电子转移的机制和精力充沛的方面，使用合成，测量和建模的方法，专注于六个明确定义的问题。在这个提议中，他确定了电子转移领域最重要的技术和概念问题，这个提议的成功将大大有助于解决这些问题。在物理有机化学中，化学反应性的研究一直是电子对转移反应的研究领域。然而，单电子转移已经吸引了越来越多的关注，其中兴趣已经涉及外层反应和更复杂的过程，其中电子转移与键断裂或键形成相结合。在这一领域的机制和反应性方面还有很多有待发现，纳尔逊教授的工作将大大有助于这些发现。电子转移反应在化学和生物学中都非常重要，例如，在光合作用和呼吸作用中发现，这是两个非常重要的生命过程。总的来说，科学作为一个整体和社会将自然受益于培训，尼尔森教授将提供年轻的科学家在化学研究的这一重要领域。有了这个奖，化学部的有机和高分子化学计划支持斯蒂芬尼尔森教授在化学系的研究活动在威斯康星州-麦迪逊大学。 Nelsen教授继续在理解电子转移反应方面处于世界领先地位。除了回答物理有机化学中的一些基本问题外，博士后和研究生还将接受重要化学反应的合成、测量和建模方面的独特培训。

With this renewal proposal the Organic and Macromolecular Chemistry Program supports the on- going work of Professor Stephen Nelsen in the Department of Chemistry at the University of Wisconsin- Madison. This work by Professor Nelsen outlines several mechanistic studies of electron transfer in various bridged donor-acceptor compounds, primarily bis-hydrazines. Professor Nelsen seeks to continue his work on the mechanistic and energetic aspects of intramolecular electronic transfer using a synthetic, measurement, and modeling approach to focus on six well-defined questions. In this proposal he has identified the most important technical and conceptual problems in the electron transfer field, and success with this proposal will go a long way toward solving these problems. Investigation of chemical reactivity in physical organic chemistry has long been the realm of electron pair transfer reactions. However, single electron transfer has attracted increasing attention where the interest has been concerned with outer- sphere reactions and with more complex processes where electron transfer is coupled with bond breaking or bond formation. There is much to be discovered in this field in terms of mechanisms and reactivity and Professor Nelson's work will go a long way toward making these discoveries. Electron transfer reactions are very important in both chemistry and biology, and are found, for example, in photosynthesis and respiration, two very important life processes. In general, science as a whole and society will naturally benefit from the training that Professor Nelsen will provide younger scientists in this important area of chemical research.With this Award, the Organic and Macromolecular Chemistry Program of the Division of Chemistry supports the research activities of Professor Stephen Nelsen in the Department of Chemistry at the University of Wisconsin- Madison. Professor Nelsen continues to be a world leader in understanding electron transfer reactions. In addition to answering some fundamental questions in physical organic chemistry, post-doctoral and graduate students will receive unique training in synthesis, measurement, and modeling of important chemical reactions.