NER: An Acoustic Tweezer for Nanoparticle Manipulation

职务名称：摘要本研究的目的是探讨利用声场对空气中纳米粒子进行三维操控的可行性。 由固态声换能器产生的声场将提供向颗粒传递机械力的非接触装置，并且通过控制力在空间中的分布，将控制颗粒的3-D位置。 将在不同的操作条件下研究悬浮、水平和旋转运动等特征。 实验和理论的努力，导致理解的物理机制的操作的纳米粒子操纵器（ATNM）的声镊将undertaken.The工作提出福尔斯分为三个广泛的活动：设备开发，理论建模和概念验证。 这三个领域并不相互排斥，将同时进行。 设备开发包括设计、制造和测试声换能器和伴随的电子设备，以有效地产生界面力。 描述粒子与换能器表面相互作用的理论模型将结合系统的纳米级复杂性和待研究系统的多个长度尺度。 这些发展将使用专用的测量技术进行验证，其中颗粒尺寸和界面力产生的各个方面将在仔细控制或模拟的实验条件下进行检查。 最后，测量的ATNM特性将与标准的光学（微米级颗粒），原子力显微镜（AFM）和近场光学显微镜（NSOM）（纳米颗粒）technology. Acoustic操纵技术，一旦开发，将补充目前的微纳米粒子操纵技术，如激光镊子，磁镊子和扫描探针显微镜。 特别地，该技术将提供用于根据纳米颗粒的尺寸、形状或相互作用性质来分离纳米颗粒的有效方法。 声操纵技术将是有效的纳米粒子，无论其光学，电学和磁学性质，因此可以在各种环境中，在不同的介质中使用。 声操纵技术的这些独特功能将显著影响纳米颗粒的表征和应用领域。 这项研究的长期目标是开发一种能够自主和可编程地操纵气体和液体中纳米颗粒的ATNM芯片。 ATNM芯片将为设计和监测涉及无机纳米粒子以及蛋白质或细胞等生物对象的各种生物化学和生物物理过程提供实验平台。

Title: An Acoustic Tweezer for Nanoparticle ManipulationAbstractThe goal of this project is to demonstrate the feasibility of using of acoustic fields for three-dimensional manipulation (3-D) of a nanoparticle in the air. An acoustic field generated by solid state acoustic transducers will provide a non-contact means of delivering a mechanical force to the particle, and by controlling the distribution of the force in space one will control the 3-D position of the particle. Features such as levitation and horizontal and rotational motions will be studied under different operating conditions. Experimental and theoretical efforts leading to understanding the physical mechanisms of operation of an Acoustic Tweezer for Nanoparticle Manipulator (ATNM) will be undertaken.The work proposed falls into three broad activities: device development, theoretical modeling and the concept validation. These three areas are not mutually exclusive and will proceed simultaneously. Device development includes design, fabrication and testing of acoustic transducers and accompanying electronics for efficient generation of interfacial forces. Theoretical models describing the interaction of a particle with the surface of a transducer will incorporate the nanoscale complexity of the system and the multiple length scales of the systems to be studied. These developments will be validated using dedicated measurement techniques in which various aspects created by particle size and interfacial forces will be examined in carefully controlled or simulated experimental conditions. Finally, the measured ATNM characteristics will be correlated with standard optical (micron-size particles), Atomic Force Microscope (AFM) and Near Field Optical Microscope (NSOM) (nanoparticles) techniques.The acoustic manipulation technique, once developed, will be complementary to current micro- and nano-particle manipulation techniques, such as laser tweezers, magnetic tweezers and scanning probe microscopes. In particular, this technique will provide an efficient method for separating nanoparticles according to their size, shape or interaction properties. The acoustic manipulation technique will be effective on nanoparticles regardless of their optical, electrical and magnetic properties, and thus can be used in various environments and in different media. These unique features of the acoustic manipulation technique will significantly impact the fields of characterization and application of nanoparticles. The long-term objective of this research is to develop an ATNM chip capable of autonomous and programmable manipulation of nanoparticles in gases and liquids. ATNM chip will provide an experimental platform for designing and monitoring various bio-chemical and bio-physical processes involving inorganic nanoparticles as well biological objects such as proteins or cells.