MRI/RUI: Acquisition of a Linux Cluster for Numerical Simulations of Excitable Media

MRI/RUI：获取用于可兴奋介质数值模拟的 Linux 集群

• 批准号: 0319555
• 负责人: Roman Zaritski
• 金额: $ 10万
• 依托单位: Montclair State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0319555&HistoricalAwards=false
• 关键词: MRI; RUI; Acquisition; Linux; Cluster

ABSTRACTProposal No. CTS-0319555Principal Investigator: R. Zaritski, Montclair State UniversityThe grant will facilitate acquisition of a Linux cluster with a total peak performance of 150 billion floating point operations per second. Tentatively, the cluster will consist of 32 dual AMD Athlon nodes interconnected by Gigabit Ethernet. Its main intended use is for numerical simulations of spiral and scroll wave interactions in excitable media. This highly multidisciplinary research project is a collaborative effort between the principal investigator, Dr. R. Zaritski (Montclair State University), and Dr. A. Pertsov (SUNY Upstate Medical University). It involves Applied and Computational Mathematics, Chemistry and Biology, Physics and Computer Science. To increase utilization, the cluster will also be used for numerical simulations of disease dynamics, an auxiliary research project headed by Dr. L. Billings (Montclair State University), and, possibly, for other auxiliary projects.Examples of excitable media include a variety of physical, chemical, and biological systems. Two most well-known examples are Belousov-Zhabotinsky (BZ) chemical reaction and electrochemical activity in the cardiac tissue. Virtually all known excitable media support special vortex-like waves known as spiral waves in two dimensions and scroll waves in three dimensions. Spiral and scroll waves in human heart correspond to cardiac arrhythmias, the leading cause of death in industrialized countries. Interacting spiral and scroll waves are believed to be the primary mechanism of fibrillation, the most deadly cardiac arrhythmia. Spiral and scroll wave interactions have been studied for many years, but are not yet well understood. Numerical simulations of such interactions are very computationally intensive and, especially in the three-dimensional case, require supercomputing resources.The broader impact of this project at Montclair State University, which is a major public, predominantly undergraduate institution serving the diverse New Jersey population, will include: enhancing the university high-performance computing infrastructure, attracting more students to hands-on multidisciplinary research, and establishing and strengthening a cross-institutional research partnership between a teaching and a research university. Eventually, computer modeling of excitable media may lead to better prediction and control of heart arrhythmias and to new computing paradigms, based on chemical reactions. Results of the proposed investigation will be disseminated through national and international professional journals and meetings.

摘要建议编号 CTS-0319555主要研究者： R. Zaritski，蒙特克莱尔州立大学这笔赠款将促进收购一个Linux集群，总峰值性能为每秒1500亿次浮点运算。该集群将由32个通过千兆以太网互连的双AMD Athlon节点组成。 它的主要用途是数值模拟的螺旋和涡卷波相互作用在可激发介质。这个高度多学科的研究项目是主要研究者R。Zaritski（蒙特克莱尔州立大学）和A. Pertsov（SUNY Upstate Medical University）. 它涉及应用和计算数学，化学和生物学，物理学和计算机科学。 为了提高利用率，该集群还将用于疾病动力学的数值模拟，这是由L。比林斯（蒙特克莱尔州立大学），并可能用于其他辅助项目。可激发介质的例子包括各种物理、化学和生物系统。两个最著名的例子是Belousov-Zhabotinsky（BZ）化学反应和心脏组织中的电化学活性。几乎所有已知的可激发介质都支持特殊的涡旋状波，称为二维螺旋波和三维涡卷波。人类心脏中的螺旋波和涡卷波对应于心律失常，心律失常是工业化国家死亡的主要原因。螺旋波和涡卷波的相互作用被认为是最致命的心律失常--纤维性颤动的主要机制。螺旋波和涡卷波的相互作用已经研究了很多年，但还没有得到很好的理解。 这种相互作用的数值模拟是非常计算密集型的，特别是在三维的情况下，需要超级计算资源。该项目在蒙特克莱尔州立大学的更广泛的影响，这是一个主要的公共，主要是本科院校服务于不同的新泽西人口，将包括：加强大学的高性能计算基础设施，吸引更多的学生动手多学科研究，以及建立和加强教学型大学和研究型大学之间的跨院校研究伙伴关系。最终，兴奋介质的计算机建模可能会导致更好地预测和控制心律失常，并导致基于化学反应的新计算范式。拟议调查的结果将通过国家和国际专业刊物和会议传播。