SBIR Phase I: DNA-Based Chemosensors for Direct Detection of Volatile Compounds

SBIR 第一阶段：用于直接检测挥发性化合物的基于 DNA 的化学传感器

• 批准号: 0319855
• 负责人: Joel White
• 金额: $ 10万
• 依托单位: CogniScent, Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-07-01 至 2004-02-29
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0319855&HistoricalAwards=false
• 关键词: SBIR; Phase; DNA; Based; Chemosensors

This Small Business Innovation Research (SBIR) Phase I project will develop a novel portable sensor array device, based directly on biological principles, for rapidly detecting, identifying, and quantifying volatile compounds in the environment. Lab and field tests show that this platform is sensitive enough to detect and discriminate the vapor signature of buried TNT-filled landmines. This SBIR Phase I project focuses on incorporating into the device a novel sensing technology that uses dye-labeled DNA to directly detect volatile chemicals with the use of state-of-the-art microarray equipment.The commercial application of the product will be as a lightweight, low-cost, hand-held volatile chemical detection system for use in security screening for the rapid detection of explosives, chemical warfare agents, and other hazardous materials. Other potential uses include medical diagnostics and environmental monitoring.

该小型企业创新研究 (SBIR) 第一阶段项目将开发一种直接基于生物学原理的新型便携式传感器阵列设备，用于快速检测、识别和量化环境中的挥发性化合物。 实验室和现场测试表明，该平台足够灵敏，可以检测和区分埋藏的 TNT 地雷的蒸气特征。 该SBIR第一阶段项目的重点是在设备中融入一种新颖的传感技术，该技术使用染料标记的DNA，通过最先进的微阵列设备直接检测挥发性化学物质。该产品的商业应用将是作为一种轻型、低成本、手持式挥发性化学物质检测系统，用于安全检查，以快速检测爆炸物、化学战剂和其他危险材料。 其他潜在用途包括医疗诊断和环境监测。