MRI/RUI: Acquisition of a Transmission Electron Microscope for Multidisciplinary Research and Education

MRI/RUI：购买透射电子显微镜用于多学科研究和教育

• 批准号: 0321070
• 负责人: T. Page Owen, Jr.
• 金额: $ 31.84万
• 依托单位: Connecticut College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0321070&HistoricalAwards=false
• 关键词: MRI; RUI; Acquisition; Transmission; Electron

A grant has been awarded to Connecticut College under the direction of Dr. T. Page Owen for the purchase of a digital transmission electron microscope (TEM) to be used by the Departments of Botany, Chemistry, Psychology and Zoology. The TEM will advance research and research training activities in cellular and materials sciences. Along with the rest of the science and math departments at the College, the programmatic offerings of the life sciences, chemistry and neurobiology are dedicated to providing its majors with an outstanding educational experience, including multidisciplinary research training and grant-supported research opportunities. The overarching philosophy in the sciences is that teaching and research with undergraduates is one unified activity.TheTEM will fulfills tremendous need for on-site and hands-on access to modern instrumentation as a research tool. Acquisition of the TEM for biological and chemical samples will have an immense intellectual impact on the productivity and quality of faculty and student experiences, bringing together faculty from four different departments into an interdisciplinary venture in ongoing and planned research projects, including: (1) the assembly and activity of the Golgi apparatus in plant cells, (2) the structure of wing muscle tissue in flightless Drosophila, (3) the control of cell division in freshwater sponges after diapause, (4) the changes in mouse astrocytes expressing a cyclin-dependent protein kinase, (5) the immunolocalization of neurotransmitters in rat brains in response to predator odor, and (6) the organization of microporous manganese oxides with layered and tunneled structures. These research plans incorporate very meaningful participation by undergraduates in faculty research. Additional research projects, through student-initiated research, will also use the new TEM. With the instrument, faculty in the different departments can also begin implementing ultrastructural experiments in laboratories of upper division cell and developmental biology, neuroscience, and physical, inorganic, and analytical chemistry courses. Additionally, thedigitally imaging capabilities of the new TEM will make surveys of cell and tissue ultrastructure possible in introductory courses.This instrument will have a broad impact on the botany, chemistry, psychology,and zoology education programs by introducing TEM into the curriculum, where it waspreviously present in a limited capacity. Experience gained through the routine hands-onoperation of modern TEM instrumentation in beginning- to advanced-level laboratories, in addition to individual research projects with faculty, will be invaluable for the students, and a critically important part of the educational process of preparing students at different levels for careers in science.

在T博士的指导下，康涅狄格学院获得了一笔赠款。页欧文购买数字透射电子显微镜（TEM）将用于植物学，化学，心理学和动物学系。 TEM将推进细胞和材料科学的研究和研究培训活动。沿着在学院的科学和数学部门的休息，生命科学，化学和神经生物学的程序产品致力于提供其专业与优秀的教育经验，包括多学科研究培训和赠款支持的研究机会。在科学的总体理念是，教学和研究与本科生是一个统一的活动。TEM将满足现场和动手访问现代仪器作为研究工具的巨大需求。 获取生物和化学样品的TEM将对教师和学生体验的生产力和质量产生巨大的智力影响，将来自四个不同部门的教师聚集在一起，共同开展正在进行和计划中的研究项目，包括：（1）植物细胞中高尔基体的组装和活动，（2）不能飞的果蝇翅膀肌肉组织的结构，（3）滞育后淡水海绵细胞分裂的控制;（4）表达细胞周期蛋白依赖性蛋白激酶的小鼠星形胶质细胞的变化;（5）捕食者气味对大鼠脑中神经递质的免疫定位;（6）具有层状和隧道结构的微孔锰氧化物的组织。这些研究计划包括非常有意义的参与大学生在教师的研究。其他研究项目，通过学生发起的研究，也将使用新的TEM。与仪器，教师在不同的部门也可以开始实施超微结构实验在实验室的上分裂细胞和发育生物学，神经科学，物理，无机和分析化学课程。此外，新TEM的数字成像能力将使细胞和组织超微结构的调查成为可能，在入门课程。这台仪器将有广泛的影响，植物学，化学，心理学和动物学教育计划，通过引入TEM课程，在那里它是以前在有限的能力。通过现代TEM仪器的日常动手操作获得的经验，在开始到先进水平的实验室，除了与教师的个人研究项目，将是非常宝贵的学生，并准备学生在不同层次的职业生涯在科学教育过程中的一个至关重要的部分。