AToL: Collaborative Research: Amphibia Tree--An Integrated Phylogenetic and Phyloinformatics Approach to the Tree of Amphibians

堪萨斯大学的琳达特鲁布博士和雷夫布朗博士获得了一笔赠款，用于研究现存两栖动物及其化石近亲的系统发育关系。 现代两栖动物是地球脊椎动物区系的重要组成部分，包括三个目：无尾目（Gymnophiona），蝾螈（Caudata）和青蛙和蟾蜍（Anura）。 尽管最近在发现和描述它们的多样性方面取得了进展，但两栖动物进化中的许多关键问题仍然没有解决，需要对进化关系进行新的分析以考虑新的发现。 此外，最近许多环境中两栖动物的减少和明显灭绝使得我们迫切需要发现和分类今天的多样性。 来自不同机构（德克萨斯大学、加州大学伯克利分校、哈佛大学和堪萨斯大学）的七名研究人员将合作解决现代两栖动物的关系。 来自活的和化石形式的解剖数据将与尽可能多的物种的一组定义的线粒体和核基因的DNA序列相结合，并将与现有的数据集相结合。 对这些大型数据集的分析将用于深入了解诸如重复的进化模式、地理模式和进化速率等问题。Trueb博士将监督化石和近代青蛙和蟾蜍的形态学研究，Brown博士将对东南亚的无尾类进行研究。了解现代两栖动物的进化历史对于制定两栖动物保护策略以及完成生命之树的脊椎动物部分至关重要。 该项目将涉及广泛的学生培训和与美国和国际同事的互动。 与公众的交流将利用网络资源，特别是AmphibiaWeb，这是一个现有的网站，将扩大和进一步发展，为专业人员和广大公众提供有关所有两栖动物物种的信息。 AmphibiaWeb还将为学生和高级专业人员提供培训机会，使他们能够更有效地交流他们的发现。

A grant has been awarded to Dr. Linda Trueb and Rafe Brown at the University of Kansas to study phylogenetic relationships of the living amphibians and their close fossil relatives. Modern Amphibians are a prominent part of the Earth's vertebrate fauna and include three orders: the caecilians (Gymnophiona), salamanders (Caudata), and frogs and toads (Anura). Despite recent advances in discovering and describing their diversity, many critical questions in amphibian evolution remain unresolved and a fresh analysis of evolutionary relationships is needed to take new discoveries into account. Furthermore, the recent decline and apparent extinction of amphibians from many environments makes it urgent that we discover and classify the diversity present today. A team of seven investigators from diverse institutions (University of Texas, University of California at Berkeley, Harvard University, and the University of Kansas) will collaborate to resolve modern amphibian relationships. Anatomical data from living and fossil forms will be combined with DNA sequences from a set of defined mitochondrial and nuclear genes for as many species as possible, and will be integrated with existing data sets. Analysis of these large data sets will be used to gain insight into such questions as repeated patterns of evolution, geographic patterns, and rates of evolution. Dr. Trueb will oversee morphological studies of fossil and Recent frogs and toads, and Dr. Brown will conduct research on anurans of Southeastern Asia. Understanding the evolutionary history of modern amphibians is critical for developing conservation strategies for amphibians as well a completing the vertebrate portion of the tree of life. The project will involve extensive student training and interaction with US and international colleagues. Communication with the public will use web resources, especially AmphibiaWeb, an existing site that will be expanded and further developed to provide information on all species of amphibians for professionals and the public at large. AmphibiaWeb will also provide training opportunities for students and senior professionals to enable them to more effectively communicate their findings.