ATOL: Collaborative Research: The Deep Scaly Project: Resolving Squamate Phylogeny Using Genomic and Morphological Approaches

ATOL：合作研究：深鳞项目：使用基因组和形态学方法解决鳞类系统发育

• 批准号: 0334967
• 负责人: Tod Reeder
• 金额: $ 64.67万
• 依托单位: San Diego State University Foundation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0334967&HistoricalAwards=false
• 关键词: ATOL; Collaborative; Research; Deep; Scaly

A grant has been awarded to Dr. Tod Reeder of San Diego State University to study the evolutionary history of squamate reptiles (lizards and snakes). With more than 7,700 species, squamates are the second largest group of vertebrates after birds. Many critical questions in squamate evolution remain unresolved, such as identification of the most primitive lineage of squamates, the origin of snakes, and the relationships of venomous snakes to other snake lineages. An international team of eight investigators from diverse institutions (Brigham Young University, Field Museum of Natural History, San Diego State University, State University of New York-Stony Brook, University of Adelaide, University of Texas-Austin, and Yale University) will collaborate to resolve squamate relationships. Anatomical data from living and fossil forms will be combined with DNA sequences from 50 genes for 142 representative squamate species. Anatomical data will be obtained using traditional methods and new high resolution X-ray scanning techniques. DNA data will be generated by incorporating new tools and databases from recent vertebrate genome projects. Computer modeling will be used to determine how data from molecular and fossil studies can best be combined to reconstruct evolutionary trees. Dr. Reeder will be one of several researchers responsible for the selection and sequencing of genes and designing the project web-site.Squamates are an important model system in biology, and understanding their evolutionary history is critical for a complete picture of vertebrate evolution and ecology. Venomous snakes pose an important threat to human safety in many parts of the world, and identification is critical for effective treatment. An innovative web-site will allow snakebite victims and medical workers to identify the venomous snakes in their area. Postdoctoral researchers and students will be involved in nearly every aspect of the project, and thus the training of many future biologists and educators will be supported.

圣地亚哥州立大学的托德里德博士获得了一笔赠款，用于研究有鳞爬行动物（蜥蜴和蛇）的进化史。 有鳞动物有7,700多种，是仅次于鸟类的第二大脊椎动物。 有鳞动物进化中的许多关键问题仍然没有解决，例如最原始的有鳞动物谱系的识别，蛇的起源，以及毒蛇与其他蛇谱系的关系。 一个由来自不同机构（杨百翰大学、菲尔德自然历史博物馆、圣地亚哥州立大学、纽约州立大学-石溪分校、阿德莱德大学、德克萨斯大学-奥斯汀分校和耶鲁大学）的8名研究人员组成的国际团队将合作解决鳞片关系。 来自活的和化石形式的解剖数据将与来自142个代表性有鳞动物物种的50个基因的DNA序列相结合。 将使用传统方法和新的高分辨率X射线扫描技术获得解剖数据。 DNA数据将通过整合最近脊椎动物基因组计划的新工具和数据库来生成。 计算机建模将用于确定如何将分子和化石研究的数据最好地结合起来，以重建进化树。 里德博士将是负责基因选择和测序以及设计项目网站的几位研究人员之一。有鳞目动物是生物学中一个重要的模式系统，了解它们的进化历史对于完整地了解脊椎动物的进化和生态学至关重要。 毒蛇在世界许多地方对人类安全构成重要威胁，识别对于有效治疗至关重要。一个创新的网站将允许蛇咬伤的受害者和医务工作者识别他们所在地区的毒蛇。 博士后研究人员和学生将参与项目的几乎每一个方面，因此将支持许多未来生物学家和教育工作者的培训。