Applications of Bismuth Compounds in Organic Synthesis

铋化合物在有机合成中的应用

• 批准号: 0350216
• 负责人: Ram Mohan
• 金额: $ 20.53万
• 依托单位: Illinois Wesleyan University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0350216&HistoricalAwards=false
• 关键词: Applications; Bismuth; Compounds; Organic; Synthesis

The focus of this research involves the development of diverse methodology for use of bismuth compounds as relatively nontoxic, low cost reagents that are insensitive to small amounts of air and moisture. Dehydration of oximes, allylations, epoxides-olefin cyclizations and the synthesis of resorcinarenes will all be carried out. Undergraduate co-workers will have an important role in this research effort that stresses the development of environmentally friendly chemistry.With this Research in Undergraduate Institutions (RUI) award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. Ram S. Mohan in the Department of Chemistry at Illinois Wesleyan. Professor Mohan will focus his research efforts on developing methodology for the use of bismuth reagents as catalysts in organic synthesis. There is potential for broader impact of the work in the use of green chemistry in the pharmaceutical industry and the project presents an excellent venue for the training of undergraduate students.

这项研究的重点是开发多种方法，用于使用铋化合物作为相对无毒，低成本的试剂，对少量空气和水分不敏感。 肟的脱水、烯丙基化、环氧化物-烯烃环化和间苯二酚芳烃的合成都将进行。 本科生同事将在这项强调环境友好化学发展的研究工作中发挥重要作用。有了这个本科生机构研究奖（RUI），有机和高分子化学计划支持Ram S博士的研究。莫汉在伊利诺伊州卫斯理大学化学系。 Mohan教授的研究重点将是开发使用铋试剂作为有机合成催化剂的方法。 在制药工业中使用绿色化学的工作有可能产生更广泛的影响，该项目为本科生的培训提供了一个很好的场所。