Sequencing the mammalian transcriptome in toto

对哺乳动物转录组进行整体测序

• 批准号: DP0988754
• 负责人: Prof Sean Grimmond
• 金额: $ 31.8万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0988754
• 关键词: Sequencing; mammalian; transcriptome; toto

The mammalian genome projects have provided a huge leap forward for biological research by giving the framework to study genes on a global scale. This project will provide human genome project scale information for every major tissue in mammals and will provide the research community with a world class resource to further genomic research. It will also investigate parts of gene regulation which have been invisible to researchers in the past. Discovering these rules will provide novel insights in pathology with a genetic component and provide a further boost to biotechnological approaches to obtain expression of specific sets of genes in model systems.

哺乳动物基因组计划为生物学研究提供了一个巨大的飞跃，为在全球范围内研究基因提供了框架。该项目将为哺乳动物的每个主要组织提供人类基因组计划规模的信息，并将为研究界提供世界级的资源，以进一步开展基因组研究。它还将研究过去研究人员看不到的基因调控部分。发现这些规则将为具有遗传成分的病理学提供新的见解，并为生物技术方法提供进一步的推动，以获得模型系统中特定基因组的表达。