A Tabletop Ultracentrifuge for Biology

用于生物学的台式超速离心机

• 批准号: 0400706
• 负责人: Marinus Pilon
• 金额: $ 3.24万
• 依托单位: Colorado State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-15 至 2006-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0400706&HistoricalAwards=false
• 关键词: Tabletop; Ultracentrifuge; Biology

This award provides partial support for the purchase of a high-speed tabletop ultracentrifuge in the Biology Department at Colorado State University. The instrument will allow: (1) fast separations, (2) the separation of many small volume samples simultaneously, and (3) analytical scale gradient centrifugation. A number of research projects in the areas of Plant Biology, Cell and Developmental Biology, Transport Physiology, and Phytoremediation will be supported by this equipment. Applications for the ultracentrifuge include: localization of transporters, receptors and regulators in sub-cellular compartments; development of transport assays; cosedimentation assays for cytoskeletal elements; separation of polysomal fractions; isolation of RNA-protein complexes; clearance of cell free extracts; and gradient centrifugation of nucleic acids. Life science education and research are at the core of the overall scholarly activity at Colorado State University, and the equipment will also enhance the experience of students both in REU programs and in upper division cell biology classes.

该奖项为科罗拉多州立大学生物系购买高速桌面超级计算机提供部分支持。 该文书将允许：（1）快速分离，（2）同时分离许多小体积样品，和（3）分析规模的梯度离心。 该设备将支持植物生物学、细胞和发育生物学、运输生理学和植物修复领域的一些研究项目。 超离心的应用包括：定位亚细胞区室中的转运蛋白、受体和调节剂;开发转运测定;细胞骨架元件的共沉降测定;分离多聚体组分;分离RNA-蛋白质复合物;清除无细胞提取物;和核酸的梯度离心。 生命科学教育和研究是科罗拉多州立大学整体学术活动的核心，这些设备也将增强学生在REU课程和上分裂细胞生物学课程中的经验。