A Tabletop Ultracentrifuge for Biology

这项奖励为科罗拉多州立大学生物系购买高速桌面超速离心机提供部分支持。该仪器将允许：(1)快速分离，(2)同时分离多个小体积样品，(3)分析规模梯度离心法。该设备将支持植物生物学、细胞和发育生物学、运输生理学和植物修复领域的一些研究项目。超速离心法的应用包括：转运体、受体和调节剂在亚细胞室的定位；运输分析的发展；细胞骨架元素的共印迹分析；多聚体部分的分离；RNA-蛋白质复合体的分离；无细胞提取物的清除；以及核酸的梯度离心法。生命科学教育和研究是科罗拉多州立大学整体学术活动的核心，这些设备还将增强学生在REU项目和高级分裂细胞生物学课程中的体验。

This award provides partial support for the purchase of a high-speed tabletop ultracentrifuge in the Biology Department at Colorado State University. The instrument will allow: (1) fast separations, (2) the separation of many small volume samples simultaneously, and (3) analytical scale gradient centrifugation. A number of research projects in the areas of Plant Biology, Cell and Developmental Biology, Transport Physiology, and Phytoremediation will be supported by this equipment. Applications for the ultracentrifuge include: localization of transporters, receptors and regulators in sub-cellular compartments; development of transport assays; cosedimentation assays for cytoskeletal elements; separation of polysomal fractions; isolation of RNA-protein complexes; clearance of cell free extracts; and gradient centrifugation of nucleic acids. Life science education and research are at the core of the overall scholarly activity at Colorado State University, and the equipment will also enhance the experience of students both in REU programs and in upper division cell biology classes.