US-UK Cooperative Research: Decarboxylation of Carboxymethyl Betaines

美英合作研究：羧甲基甜菜碱的脱羧

• 批准号: 0405210
• 负责人: David Forbes
• 金额: $ 2.38万
• 依托单位: University of South Alabama
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0405210&HistoricalAwards=false
• 关键词: US; UK; Cooperative; Research; Decarboxylation

0405210ForbesThis three-year US-UK cooperative research award supports visits by undergraduate students and the principal investigator to the University of East Anglia. David Forbes of the University of South Alabama and his UK counterpart, Robert Stockman, propose to conduct chemical studies of sulfur ylides and apply their methodologies to medicinally important compounds. Intellectual Merit: Undergraduates at Alabama will participate in several research projects during three-month stays in East Anglia. They will focus on the use of chiral sulfinyl imines as receptors using a methylidene transfer approach and stidy sulfur ylides in model systems. The research project's ultimate goal is to develop a complete synthesis of a system of biological and medicinal importance. Broader Impacts: This international collaboration is highly complementary and combines the expertise of investigators in synthetic organic chemistry and their different synthetic methodologies. It also provides an international research and training experience to undergraduate researchers from a predominantly undergraduate US institution in an EPSCoR state.

0405210福布斯这个为期三年的美英合作研究奖支持本科生和首席研究员访问东英吉利大学。 南亚拉巴马大学的大卫福布斯和他的英国同行罗伯特斯托克曼提议对硫叶立德进行化学研究，并将他们的方法应用于具有药用价值的化合物。智力优势：亚拉巴马的本科生将在东安格利亚停留三个月期间参加几个研究项目。 他们将集中在使用手性亚磺酰亚胺作为受体使用亚甲基转移方法和stidy硫叶立德在模型系统。 该研究项目的最终目标是开发一个具有生物学和医学重要性的系统的完整合成。更广泛的影响：这种国际合作具有高度互补性，结合了合成有机化学研究人员的专业知识及其不同的合成方法。 它还为来自EPSCoR州的主要本科美国机构的本科研究人员提供国际研究和培训经验。