Organometallic Chemistry at the Edge of Polycyclic Aromatic Carbon Compounds

密苏里大学哥伦比亚分校化学系保罗·R·夏普博士因其在多环芳香碳化合物边缘的有机金属化学方面的工作而得到国家科学基金会化学部无机、生物无机和有机金属化学项目的支持。工作将集中在第10族(镍、钯、铂)配合物的合成及其在多环芳香化合物的衍生化和合成中的应用。将研究四元和五元金属环的稳定性和反应化学。镍催化合成四苯类化合物(包括手性四苯类)的研究将发展成为一种通用的催化方法。冠烯和冠烯金属循环化学的发展将继续。多环芳香碳化合物在许多化学和技术领域的普遍存在支持了本项目工作将带来的对衍生化和合成的选择性和一般性方法的需要。多环芳香碳化合物很重要或可能在未来发挥重要作用的领域包括但不限于电子(纳米管、分子线、有机半导体)、太阳能转换(太阳能电池)、医学研究(荧光探针、致癌)和结构材料(复合材料)。因此，本提案中描述的化学物质有可能对我们的社会产生重大影响。此外，本科生、研究生和博士后助理将受益于有机和有机金属/无机化学方面的培训。从历史上看，PI实验室的毕业生中约有一半是女性。

Dr. Paul R. Sharp, Department of Chemistry, University of Missouri at Columbia, is supported by the Inorganic, Bioinorganic and Organometallic Chemistry program of the Division of Chemistry, National Science Foundation, for his work on the organometallic chemistry at the edge of polycyclic aromatic carbon compounds. Work will focus on the synthesis of group 10 (Ni, Pd, Pt) complexes and their use in the derivatization and synthesis of polycyclic aromatic compounds. The stability and reaction chemistry of 4-membered and 5-membered metallacycles will be studied. The Ni mediated synthesis of tetraphenylenes (including chiral tetraphenylenes) through 5-membered nickelacycles will be investigated and will be developed into a general catalytic method. Development of coronene and corannulene metallacycle chemistry will continue.The prevalence of polycyclic aromatic carbon compounds across many areas of chemistry and technology supports a need for selective and general methods for derivatization and synthesis that the work of this project will bring. Fields where polycyclic aromatic carbon compounds are important or may play an important future roll include but are not limited to electronics (nanotubes, molecular wires, organic semiconductors), solar energy conversion (solar cells), medical research (fluorescent probes, carcinogenisis), and structural materials (composites). Thus, the chemistry described in this proposal has the potential for a large impact on our society. In addition, the undergraduate students, graduate students, and postdoctoral associates will benefit from training in both organic and organometallic/inorganic chemistry. Historically, approximately half of the graduates from the PI's laboratory have been women.