Patient-Specific Mathematical Models of the Heart for Simulation-Based Medical Planning

用于基于模拟的医疗规划的患者特定心脏数学模型托马斯·J·R·休斯（Thomas J. R. Hughes），首席研究员德克萨斯大学奥斯汀分校摘要这项研究将致力于创建第一个患者特定的人类心脏计算模型。 这些模型将构成“预测医学”过程的第一步，根据类似于现代工程设计过程的预测结果来规划、分析和优化干预措施。智力优势这项研究需要综合最先进的方法，并开发医学成像数据采集、实体建模、网格生成、阀门建模和模拟方面的新程序。更广泛的影响该研究的最终目标是为心脏病专家和心血管外科医生提供极大改进的技术来治疗心血管疾病，从而降低发病率和死亡率，降低再手术率，并缩短术后恢复时间。

Patient-Specific Mathematical Models of the Heart for Simulation-Based Medical PlanningThomas J. R. Hughes, Principal InvestigatorThe University of Texas at AustinAbstractThe proposed research will endeavor to create the first patient-specific, computational models of the human heart. The models will constitute the first step in the process of "predictive medicine," in which interventions are planned, analyzed and optimized, based on predicted outcomes analogous to the design process of modern engineering. Intellectual MeritThe research will require the synthesis of state-of-the-art methodologies and development of new procedures in medical imaging data acquisition, solid modeling, mesh generation, valve modeling, and simulation. Broader ImpactThe ultimate goal of the research is to provide cardiologists and cardiovascular surgeons with vastly improved technologies to treat cardiovascular disease, resulting in lower morbidity and mortality, reduced re-operative rates, and lessened post-operative recovery time.