STTR Phase I: A Novel Electrospray Ionization Ion Mobility Spectrometer for Real-Time Detection of Biotoxins and Other Proteins

STTR 第一阶段：用于实时检测生物毒素和其他蛋白质的新型电喷雾电离离子淌度光谱仪

• 批准号: 0419876
• 负责人: Thomas Coleman
• 金额: $ 10万
• 依托单位: dTEC Systems L.L.C.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2005-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0419876&HistoricalAwards=false
• 关键词: STTR; Phase; Novel; Electrospray; Ionization

This Small Business Technology Transfer (STTR) Phase I research project will demonstrate aninnovative application of ion mobility spectroscopy (IMS) and electrospray ionization (ESI) aimed at separation and detection of biologically active macromolecules in environmental and food product sample matrices. This innovative application of ESI-IMS will enable real time aqueous phase measurement of protein bio-toxins and other proteins of public health significance without the need for expensive diagnostic reagent additions or complex sample preparation procedures. The commercial application of this project will be in the areas of homeland security, environmental monitoring and food safety.

这个小企业技术转让（STTR）第一阶段研究项目将展示离子迁移谱（IMS）和电喷雾电离（ESI）的创新应用，旨在分离和检测环境和食品样品基质中的生物活性大分子。ESI-IMS的这一创新应用将使蛋白质生物毒素和其他具有公共卫生意义的蛋白质的真实的实时水相测量成为可能，而无需添加昂贵的诊断试剂或复杂的样品制备程序。该项目的商业应用将在国土安全、环境监测和食品安全领域。