Acquisition of a LaserScissor Workstation for Studies in Reproductive Biology and Research in Superconductivity

购买激光剪刀工作站用于生殖生物学研究和超导研究

• 批准号: 0421441
• 负责人: Dessie Underwood
• 金额: --
• 依托单位: California State University-Long Beach Foundation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0421441&HistoricalAwards=false
• 关键词: Acquisition; LaserScissor; Workstation; Studies; Reproductive

This award supports the acquisition of a laser capture microscope to be used by several investigators at California State University, Long Beach for non-contact laser capture of tissues, cells, and chromosomes. The instrument will also be used in physics as a patterning tool on high temperature superconducting thin films and devices. Specific research projects include: (1) fluorescence in situ hybridization (FISH) studies aimed at examining the identity and stability of chromosomes involved in lagging during spermatogenesis and those that form micronuclei in the sperm bundles of a butterfly (Eucheira socialis), (2) investigations of structure-specific gene expression in seasonally-regressed ovaries of Siberian hamsters (Phodopus sungorus), and (3) patterning of high temperature superconducting cuprate thin films and devices to investigate their conductive properties using variable temperature scanning laser microscopy. All faculty teach and conduct research at the minority-serving institution of CSU Long Beach. They have active research programs that involve primarily undergraduates. Using lasers for microdissection and patterning is a relatively new advance in microscopy and as of yet there are few institutions with such equipment. The laboratory work entailed in this project will provide valuable training for students with state-of-the-art equipment.

该奖项支持购买激光捕获显微镜，供加州州立大学长滩分校的几位研究人员使用，以非接触式激光捕获组织、细胞和染色体。 该仪器还将在物理学中用作高温超导薄膜和器件的图案化工具。 具体的研究项目包括：（1）荧光原位杂交（FISH）研究，旨在检查精子发生过程中滞后的染色体以及在蝴蝶（Eucheira Socialis）精子束中形成微核的染色体的身份和稳定性，（2）研究西伯利亚仓鼠（Phodopus）季节性退化卵巢中结构特异性基因表达 sungorus），以及（3）高温超导铜酸盐薄膜和器件的图案化，以使用变温扫描激光显微镜研究其导电性能。 所有教师都在科罗拉多州立大学长滩分校的少数族裔服务机构中教学和开展研究。他们有活跃的研究项目，主要涉及本科生。 使用激光进行显微切割和图案化是显微镜技术的一项相对较新的进步，但迄今为止，拥有此类设备的机构很少。该项目所需的实验室工作将为拥有最先进设备的学生提供宝贵的培训。