STTR PHASE I: Nano-Porous Glass-Coated Amorphous Metal Wires for Integrated Solid-Phase Microextraction Devices

STTR 第一阶段：用于集成固相微萃取装置的纳米多孔玻璃涂层非晶金属线

• 批准号: 0441635
• 负责人: William LaCourse
• 金额: $ 9.8万
• 依托单位: Santanoni Glass and Ceramics, Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0441635&HistoricalAwards=false
• 关键词: STTR; PHASE; Nano; Porous; Glass

This Small Business Technology Transfer (STTR) Phase I project will develop glass-coated amorphous metal (GCAM) fibers in which the glass coating is porous on the nano-scale level. Thermal treatments would be used to produce phase separation in the coating. The soluble component of the glass would be leached, leaving behind a porous skeleton of the non-soluble phase. The porous GCAM fibers will be employed as solid-phase micro-extraction (SPME) devices for the sampling of analytes such as pharmaceuticals and biomolecules from liquid matrices and volatile organic compounds from gaseous matrices. The GCAM fiber is unique in that the metal core can be heated via magnetic induction, allowing for rapid heating of the porous coating and rapid analyte desorption. The commercial application of this project will be in industrial and environmental monitoring, and in various security applications. The proposed technology will facilitate rapid, in-situ release of key samples for analysis from monitoring devices following field collection and transfer to laboratory based equipment such as gas chromatographs. In contrast, current SPME devices require external heating to desorb the analyte.

这个小企业技术转让（STTR）第一阶段项目将开发玻璃涂层非晶金属（GCAM）纤维，其中玻璃涂层在纳米级上是多孔的。热处理将用于在涂层中产生相分离。玻璃的可溶性成分将被沥滤，留下不溶性相的多孔骨架。多孔GCAM纤维将用作固相微萃取（SPME）装置，用于从液体基质中采样分析物，如药物和生物分子，以及从气体基质中采样挥发性有机化合物。GCAM纤维的独特之处在于金属芯可以通过磁感应加热，从而允许快速加热多孔涂层和快速分析物解吸。该项目的商业应用将在工业和环境监测以及各种安全应用中。拟议的技术将有助于在现场收集并转移到气相色谱仪等实验室设备后，从监测装置中快速就地释放关键样品进行分析。相比之下，目前的SPME装置需要外部加热来解吸分析物。