Operational Support for the Ambystoma Genetic Stock Center

该奖项为从印第安纳州大学（IU）到肯塔基州大学（UKY）的Ambystoma mexicanum（通常称为axlotyl）的活体收集提供支持。 该奖项还将支持在2005年夏季完成搬迁后继续运作。 该系列最初于几十年前在IU建立，是一个具有历史意义的资源，提供了在生物研究中积极和广泛使用的动物。最近和正在进行的基因组资源的蝾螈和其他密切相关的物种的发展，预计将促进继续在Ambystoma作为一个强大的非哺乳动物脊椎动物模型系统的兴趣。 最值得注意的是，蝾螈被研究是因为它们在脊椎动物中是独一无二的，能够完美地再生许多身体部位。 这些包括脊髓，四肢，下巴和尾巴，所有这些都可以在胚胎，幼虫和成年生活中的任何时候再生。将收藏品搬迁到英国将巩固目前正在为Ambystoma研究社区开发的基因组和生物信息学资源的活种群资源。该系列不仅将继续支持蝾螈是最佳脊椎动物模型系统的传统研究领域，还将继续在促进K-12教育和公共宣传工作中使用该生物体方面发挥积极作用。

This award provides support for the move of a living collection of Ambystoma mexicanum, commonly called the axlotyl, from Indiana University (IU) to the University of Kentucky (UKY). The award will also support continued operation of the collection once the move is completed in the summer of 2005. The collection, originally established many decades ago at IU, is a historically significant resource that provides animals used actively and widely in biological research. The recent and ongoing development of genome resources for the axolotl and other closely related species is expected to foster continued interest in Ambystoma as a powerful nonmammalian vertebrate model system. Most notably, axolotls are studied because they are unique among vertebrates in being able to perfectly regenerate numerous body parts. These include the spinal cord, limbs, jaw, and tail, all of which can be regenerated at any point during embryonic, larval, and adult life. Relocation of the collection to the UKY will consolidate the living stock resource with genome and bioinformatics resources currently being developed for the Ambystoma research community. The collection will not only continue to enable traditional research areas where the axolotl is the best vertebrate model system, it will also continue to take an active role in facilitating use of the organism in K-12 education and public outreach efforts.