LSCBR: Operational Support for the Ambystoma Genetic Stock Center

该奖项将支持肯塔基大学生活的墨西哥Ambystoma micianum，通常被称为axlotyl的继续运营。这些藏品最初是几十年前在印第安纳大学建立的，是一种具有重要历史意义的资源，提供了在生物研究中活跃和广泛使用的动物。随着Axolotl和其他密切相关物种基因组资源的不断发展，预计Ambystoma作为一种强大的非哺乳动物脊椎动物模型系统将继续受到关注。最值得注意的是，研究Axolotl是因为它们在脊椎动物中是独一无二的，能够完美地再生许多身体部位。这些器官包括脊髓、四肢、颌骨和尾巴，所有这些器官在胚胎、幼年和成年期间的任何时候都可以再生。将藏品迁往英国将巩固活的种群资源，以及目前正在为Ambystoma研究社区开发的基因组和生物信息学资源。该藏品不仅将继续支持传统的研究领域，使axolotl是最好的脊椎动物模型系统，它还将继续在促进在K-12教育和公共宣传工作中使用该有机体方面发挥积极作用。

This award will support continued operation of the living collection of Ambystoma mexicanum, commonly called the axlotyl at the University of Kentucky. The collection, originally established many decades ago at IU, is a historically significant resource that provides animals used actively and widely in biological research. The ongoing development of genome resources for the axolotl and other closely related species is expected to foster continued interest in Ambystoma as a powerful non mammalian vertebrate model system. Most notably, axolotls are studied because they are unique among vertebrates in being able to perfectly regenerate numerous body parts. These include the spinal cord, limbs, jaw, and tail, all of which can be regenerated at any point during embryonic, larval, and adult life. Relocation of the collection to the UKY will consolidate the living stock resource with genome and bioinformatics resources currently being developed for the Ambystoma research community. The collection will not only continue to enable traditional research areas where the axolotl is the best vertebrate model system, it will also continue to take an active role in facilitating use of the organism in K-12 education and public outreach efforts.