Interfacial chemistry and 3-D analysis of interfaces of implants and osteoporotic bone ((05) M05)

M5项目的重点是骨、骨细胞和骨/生物材料界面的质谱成像。在第二期资助期内，多孔钛合金内表面的等离子体功能化将完成。除了对骨质量本身的研究外，药物在生物材料中的检测和释放以及在骨内的分散也是重要的问题。对T项目的样本进行了研究。此外，还将进行骨细胞对药物和生物材料成分摄取的模型研究。

Project M5 focuses on mass spectrometry imaging of bone, bone cells and the bone/biomaterial interface. The in funding period 2 initiated plasma functionalization of the inner surfaces of porous titanium alloys shall be completed. Alongside the investigation of the bone quality itself, drug detection and release from the biomaterial as well as dispersion within bone are important issues. Studies are carried out on samples from the T projects. In addition, model studies on bone cells concerning drug and biomaterial components uptake will be performed.