MRI: Acquisition of A New 300 MHz NMR for Research and Student Training

MRI：获取新的 300 MHz NMR 用于研究和学生培训

• 批准号: 0520982
• 负责人: Neil Glagovich
• 金额: $ 22.36万
• 依托单位: Central Connecticut State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-08-01 至 2009-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0520982&HistoricalAwards=false
• 关键词: MRI; Acquisition; New; 300; MHz

With support from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at Central Connecticut State University will acquire a 300 MHz nuclear magnetic resonance (NMR) Spectrometer. This equipment will enable researchers to carry out studies on a) the synthesis of chiral palladium(0) catalysts for the enantiomeric reduction of unsaturated ketones to chiral allylic alcohols; b) the synthesis of macrocyclic synthetic receptors to be used in chiral HPLC column manufacture; c) synthesis of many symmetric and asymmetric thienyl derivatives of benzil and benzoin; d) the kinetics of hydration of the ligand di-2-pyridyl ketone in the presence of first-row transition metals. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic chemistry and polymer chemistry.

在主要研究仪器（MRI）计划的支持下，中央康涅狄格州立大学化学系将获得一台300 MHz核磁共振（NMR）光谱仪。该设备将使研究人员能够进行以下研究：a）合成手性钯（0）催化剂，用于将不饱和酮对映体还原为手性烯丙醇; B）合成用于手性HPLC柱制造的大环合成受体; c）合成苯偶酰和苯偶姻的许多对称和不对称噻吩基衍生物; d）在第一行过渡金属存在下配体二-2-吡啶基酮的水合动力学。核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对合成有机化学和聚合物化学产生影响。