Acquisition of High Throughput Genetic Analysis Instruments

在沙里亚尔·基尼安博士的指导下，向北达科他州立大学(北达科他州立大学)授予了一笔赠款，用于部分支持北达科他州州立大学的一个中央高通量遗传分析设施。现代遗传学/基因组学中新工具和相关技术的出现提供了一个令人兴奋的机会，将遗传发现和微小DNA分子的检测高通量地整合到植物遗传学的各个方面。这一设施将形成一个强大的调查高通量研究工具，并提高NDSU研究人员了解这些问题的分子遗传学基础并及时解决这些问题的能力。NDSU高通量遗传分析设施的开发将使研究人员能够筛选大型反向遗传集合，以鉴定和表征基因突变，开发高分辨率的染色体和/或染色体区域图，用于物理作图和基因克隆，在大种群中进行基因测试和选择，以表征不同遗传背景和环境胁迫下的基因行为，将关联图谱技术应用于基因发现，分析环境中的植物病原体或当它们与寄主相互作用时，并检测食品样本中的生物污染物及其对人类健康和营养的影响。南洋理工大学的研究人员致力于将所涉及的方法和产生的数据纳入各级学生的培训和教育中，为他们提供在就业市场上成功竞争所需的最先进的科学和技能。这些设备将影响一组非常大的项目，这些项目来自南洋理工大学校园内七个以上部门。通过多次合作，这种设备可能也会影响较小区域大学和学院的大量项目。南洋理工大学的教职员工和推广服务帮助培训和教育了一大批传统和非传统学生，包括高中生和教师、本科生、研究生、博士后科学家、部落大学生、作物顾问、种植者和各种作物改良协会的成员。

A grant has been awarded to North Dakota State University (NDSU) under the direction of Dr. Shahryar Kianian for partial support of a central high-throughput genetic analysis facility at NDSU. The advent of new tools and associated technologies in modern genetics/genomics has provided an exciting opportunity to integrate genetic findings and detection of minute DNA molecules to all aspects of plant genetics on a high-throughput scale. This facility will form a powerful investigative high-throughput research tool, and enhance the capability of NDSU researchers to understand the molecular genetic basis of these problems and address them in a timely manner.Development of the NDSU high-throughput genetic analysis facility will allow researchers to screen large reverse genetic collections for identification and characterization of mutations in genes, develop high-resolution maps of chromosomes and or chromosomal regions for physical mapping and gene cloning, conduct genetic testing and selection in large populations for characterization of gene action in different genetic backgrounds and environmental stresses, apply association mapping techniques to gene discovery, analyze plant pathogens in the environment or as they interact with their hosts, and detect bio-contaminants in food samples and their impact on human health and nutrition. NDSU researchers are committed to incorporating the methodologies involved and data generated into the training and education of students at all levels, providing them with access to state-of-the-art science and skills needed to successfully compete in the job market. The equipment will impact a very large group of projects from more than seven departments across the NDSU campus alone. Through numerous collaborations this equipment can potentially impact a large number of projects in smaller regional universities and colleges as well. NDSU faculty and extension services help train and educate a large group of traditional and non-traditional students including high school students and teachers, undergraduate students, graduate students, postdoctoral scientists, tribal college students, crop consultants, growers, and members of various crop improvement associations.