SBIR Phase I: Combinatorial Nano-Synthesis and Informatics for Rapid Discovery of Advanced Scintillators

SBIR 第一阶段：组合纳米合成和信息学，用于快速发现先进闪烁体

• 批准号: 0538979
• 负责人: Ted Sun
• 金额: --
• 依托单位: LS TECHNOLOGIES
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0538979&HistoricalAwards=false
• 关键词: SBIR; Phase; Combinatorial; Nano; Synthesis

The Small Business Innovation Research Phase I project is to develop and validate a set of novel combinatorial nano-synthesis and informatics tools, which can lead to the rapid search and discovery of efficient and fast scintillators for next generation detectors with increased energy and temporal resolutions, sensitivity, stopping power for various security inspection and commercial applications. Scintillators are the "eyes" of many modern security inspection systems that utilize high-energy photon or neutron. The recent demands for faster, more accurate and sensitive detectors are driving the need for scintillators that are heavy, fast, efficient, and high-energy resolution. Unfortunately, no single scintillator currently known has all these desirable properties. There are 2 major innovations in this project: 1. Rapid deposition and synthesis of a large collection of different nano-crystalline scintillators from multiple nanometer-layers thin film precursors; 2. Powerful and custom scintillator database which integrates data mining functions and informatics for the discovery of "scintillator leads" and for guiding the combinatorial scintillator process. The combinatorial process developed in the project will significantly accelerate the R&D rate for superior scintillators and benefit the development of security detectors. More sensitive scintillator will enable more accurate and faster detection of potential threats. In addition, there is huge commercial potential for advanced scintillators in modern medical diagnostics systems such as digital radiography, mammography; fluoroscopic imaging, angiography, SPECT, PET etc. Such medical systems, leveraged by advanced scintillators as sensors, have combined annual revenue of $10 Billion of global market. Finally, the advanced scintillators discovered can proliferate into many other commercial products in manufacturing and in search for natural resources. For example, in X-ray inspection systems for industrial non-destructive evaluation (NDE), more sensitive scintillators will enable better and deeper detection of defects for quality control in manufacturing process.

小企业创新研究第一阶段项目是开发和验证一套新颖的组合纳米合成和信息学工具，这些工具可以导致快速搜索和发现用于下一代探测器的高效和快速闪烁体，具有更高的能量和时间分辨率、灵敏度、阻止各种安全检查和商业应用的能力。闪烁体是许多利用高能光子或中子的现代安检系统的“眼睛”。最近对更快、更准确和更灵敏的探测器的需求推动了对重型、快速、高效和高能量分辨率闪烁体的需求。不幸的是，目前已知的任何一种闪烁体都不具有所有这些理想的特性。该项目有两个主要创新：1.从多纳米层薄膜前驱体快速沉积和合成大量不同的纳米晶体闪烁体；2.强大的定制闪烁体数据库，集成了数据挖掘功能和信息学，用于发现“闪烁体引线”和指导组合闪烁体过程。该项目开发的组合工艺将显著加快优质闪烁体的研发速度，并有利于安全探测器的发展。更灵敏的闪烁体将能够更准确、更快地检测到潜在的威胁。此外，先进的闪烁体在现代医疗诊断系统中具有巨大的商业潜力，如数字放射照相、乳房X光照相、荧光成像、血管造影术、SPECT、PET等。这些医疗系统与先进的闪烁体作为传感器相结合，在全球市场的年收入总计达到100亿美元。最后，发现的先进闪烁体可以在制造和寻找自然资源方面扩散到许多其他商业产品中。例如，在用于工业无损评估(NDE)的X射线检测系统中，更灵敏的闪烁体将能够更好、更深入地检测制造过程中的质量控制缺陷。