Ecology and Evolution of a Novel Bacterial Symbiont Causing Cytoplasmic Incompatibility

导致细胞质不相容的新型细菌共生体的生态学和进化

• 批准号: 0542961
• 负责人: Martha Hunter
• 金额: --
• 依托单位: University of Arizona
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2010-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0542961&HistoricalAwards=false
• 关键词: Ecology; Evolution; Novel; Bacterial; Symbiont

Insects and their relatives are commonly infected with maternally inherited bacteria that spread by manipulating the reproduction of their hosts. A common type of reproductive manipulation is cytoplasmic incompatibility (CI), in which bacteria cause infected males to be incompatible with uninfected females. This incompatibility sabotages the reproduction of uninfected females. Previously, only the bacterium Wolbachia was thought to cause this kind of manipulation. However, the recently discovered bacterium Cardinium also causes CI. This project is the first ecological study of Cardinium and will test models of how this bacterium spreads in its wasp host Encarsia pergandiella, an important biological control agent of the agricultural pest, sweetpotato whitefly. This project will also examine CI in a host infected with both Wolbachia and Cardinium, Encarsia inaron, the primary biological control agent of ash whitefly, a pest of ornamental trees in the US. The study will examine interactions between the two bacteria, and their individual and combined effects on the host. The study will determine if either, or both bacteria cause CI, and if they are mutually incompatible. This research will contribute to a better understanding of how two lineages of CI bacteria spread and affect their hosts. There is much interest in the potential of CI bacteria to suppress pests and disease agents. Broader impacts of this research include applications for management of agricultural pests and prevention of human diseases that are transmitted by insects and ticks, such as malaria and Lyme disease. This research will also contribute to education by training graduate and undergraduate students.

昆虫及其近亲通常感染母系遗传细菌，这种细菌通过操纵宿主的繁殖来传播。一种常见的生殖操作类型是细胞质不亲和(CI)，即细菌导致受感染的雄性与未受感染的雌性不相容。这种不亲和性破坏了未感染的雌性动物的繁殖。此前，只有沃尔巴克氏菌被认为会导致这种操纵。然而，最近发现的细菌Carddium也会引起CI。该项目是Carddium的第一个生态学研究，将测试这种细菌如何在其黄蜂宿主Encarsia pergandiella中传播的模型，Encarsia pergandiella是农业害虫甘薯粉虱的重要生防剂。该项目还将在同时感染Wolbachia和Carddium的宿主中检测CI，Encarsia inaron是美国观赏树木的害虫--烟粉虱的主要生防剂。这项研究将研究这两种细菌之间的相互作用，以及它们对宿主的单独和联合影响。这项研究将确定是否有一种细菌或两种细菌引起CI，以及它们是否相互不相容。这项研究将有助于更好地了解两种CI细菌是如何传播和影响宿主的。CI细菌抑制害虫和病原体的潜力引起了人们的极大兴趣。这项研究的更广泛影响包括应用于农业病虫害管理和预防由昆虫和扁虱传播的人类疾病，如疟疾和莱姆病。这项研究还将通过培养研究生和本科生来为教育做出贡献。