CAREER: The Interactions of Natural Organic Matter with Biomembranes

职业：天然有机物与生物膜的相互作用

• 批准号: 0547982
• 负责人: Robert Cook
• 金额: $ 60.8万
• 依托单位: Louisiana State University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-02-01 至 2013-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0547982&HistoricalAwards=false
• 关键词: CAREER; Interactions; Natural; Organic; Matter

With the support of the Analytical and Surface Chemistry Program, Professor Cook and his coworkers at LSU and Southern University are examining the interactions of environmental natural organic matter with biomembranes. Using a combination of NMR and fluorescence spectroscopy, the mechanism of interaction of natural organic matter with biomembrane materials is being determined. This information will help to determine how these interactions affect the permeability of biomembranes to environmental pollutants, and thus the availability of pollutants to living systems. Students are being trained in the analysis of large and complex ecosystems, and undergraduate and graduate students are teaming with local high school environmental science classes to obtain this information. This work will broadly impact fundamental knowledge in areas of ecotoxicology and bioremediation. The results of this work have implications for the design of remediation and water treatment technologies. Using detailed spectroscopic studies of environmentally relevant samples, Professor Cook and his colleagues at LSU and Southern University are examining the permeability of biomembranes to ecological pollutants. Information from this work will be important in developing models for pollutant transport in animal lung tissue, as well as in the development of remediation strategies. Graduate students, undergraduates, and a diverse population of local high school students are involved in this work.

在分析和表面化学计划的支持下，库克教授和他在路易斯安那州立大学和南方大学的同事正在研究环境天然有机物与生物膜的相互作用。 利用核磁共振和荧光光谱的结合，天然有机物与生物膜材料的相互作用机制正在确定。 这些信息将有助于确定这些相互作用如何影响生物膜对环境污染物的渗透性，从而确定污染物对生命系统的可用性。 学生们正在接受大型复杂生态系统分析方面的培训，本科生和研究生正在与当地高中环境科学班合作，以获得这些信息。 这项工作将广泛影响生态毒理学和生物修复领域的基础知识。 这项工作的结果有影响的补救和水处理技术的设计。通过对环境相关样本的详细光谱研究，库克教授和他在路易斯安那州立大学和南方大学的同事们正在研究生物膜对生态污染物的渗透性。 这项工作的信息将是重要的，在开发模型的污染物在动物肺组织中的传输，以及在制定补救策略。 研究生、本科生和当地高中生的各种人群都参与了这项工作。