SGER: Radiationless Magnetic Resonance Imaging

SGER：无辐射磁共振成像

• 批准号: 0550054
• 负责人: Alexej Jerschow
• 金额: $ 11.05万
• 依托单位: New York University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0550054&HistoricalAwards=false
• 关键词: SGER; Radiationless; Magnetic; Resonance; Imaging

In this Small Grant for Exploratory Research (SGER), funded by the Experimental Physical Chemistry Program of the Chemistry Division, Prof. Alexej Jerschow of New York University and his graduate research students will investigate the possibility of using the measured nuclear spin-noise in magnetic resonance imaging (MRI) studies. The goal is to be able to obtain one- two- and three-dimensional images of materials without the application of radio-frequency radiation.MR imaging is a powerful method that allows one to obtain images of the interiors of opaque objects. It is useful in looking at non-living material systems (e.g. polymers), and it has become a very valuable medical diagnostic tool for non-invasive imaging of living subjects. As the magnetic field strengths of MRI instruments increase (for obtaining better image contrast), the amount of radio-frequency radiation that must be dumped into the sample increases, with measurable effects (heating). The promise of the method is that it may allow one to obtain MR images, without the need for radio-frequency excitation. This would allow the acquisition of medical images without exposing the subject to large amounts of radio-frequency radiation. In addition, thermally sensitive materials (e.g. explosives) could be imaged safely.

在这项由化学系实验物理化学计划资助的探索性研究小额资助（SGER）中，纽约大学的Alexej Jerschow教授和他的研究生将研究在磁共振成像（MRI）研究中使用测量的核自旋噪声的可能性。 其目标是能够在不应用射频辐射的情况下获得材料的一维、二维和三维图像。MR成像是一种强大的方法，可以获得不透明物体内部的图像。 它在观察非生命材料系统（例如聚合物）时很有用，并且它已经成为一种非常有价值的医学诊断工具，用于活体的非侵入性成像。 随着MRI仪器磁场强度的增加（为了获得更好的图像对比度），必须倾倒到样品中的射频辐射量增加，并产生可测量的影响（加热）。 该方法的承诺是，它可以允许获得MR图像，而不需要射频激励。 这将允许在不使受试者暴露于大量射频辐射的情况下获取医学图像。 此外，热敏材料（例如爆炸物）也可以安全地成像。