GRK 1721: Integrated Analysis of Macromolecular Complexes and Hybrid Methods in Genome Biology

GRK 1721：基因组生物学中大分子复合物和混合方法的综合分析

• 批准号: 178567888
• 金额: --
• 依托单位: Ludwig-Maximilians-Universität München (LMU)
• 依托单位国家: 德国
• 项目类别: Research Training Groups
• 财政年份: 2012
• 资助国家: 德国
• 起止时间: 2011-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/178567888?language=en
• 关键词: GRK; 1721; Integrated; Analysis; Macromolecular

Research in molecular biology moves towards the analysis of complexity. We meet this development with the unique and competitive training and research network GRK1721. Our doctoral researchers decipher the structures and mechanisms of "complex macromolecular systems" in genome biology. GRK1721 is designed to tackle the next level of structure-functionsystem analysis of macromolecular complexes by integrating multi-scale approaches in life science, bridging previously separated disciplines in structural protein science, and training scientists in the emerging field of hybrid methods. Our research and training program will enable cross-disciplinary doctoral projects to address the structure, mechanism and molecular regulation of both transient and modular macromolecular complexes in genome biology. Our successful credit-based training and mentoring program with required and optional activities allows the doctoral researchers to tailor the curriculum according to their individual needs and project requirements. A core part will be advanced methods workshops that facilitate cross-disciplinary research and development of project specific hybrid approaches. We believe that the GRK1721 will help to train a new generation of scientists that are capable to successfully tackle future challenges in structural genome biology.

分子生物学的研究趋向于复杂性的分析。我们通过独特而有竞争力的培训和研究网络GRK1721来满足这一发展。我们的博士生研究人员破译了基因组生物学中“复杂大分子系统”的结构和机制。GRK1721旨在通过整合生命科学中的多尺度方法，在结构蛋白质科学中连接以前分离的学科，并在新兴的杂交方法领域培训科学家，来解决大分子复合体结构-功能系统分析的下一个层次。我们的研究和培训计划将使跨学科的博士项目能够解决基因组生物学中瞬时和模块化大分子复合体的结构、机制和分子调控。我们成功的以学分为基础的培训和指导计划，包括必要和可选活动，允许博士研究人员根据他们的个人需求和项目要求定制课程。核心部分将是促进跨学科研究和开发特定于项目的混合方法的先进方法讲习班。我们相信，GRK1721将有助于培养能够成功应对未来结构基因组生物学挑战的新一代科学家。