US-Africa Advanced Studies Institute on Mathematical Modeling of Infectious Disease in Africa; Cape Town, South Africa, June 2007

美非非洲传染病数学模型高级研究所；

• 批准号: 0629720
• 负责人: Fred Roberts
• 金额: --
• 依托单位: Rutgers University New Brunswick
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2009-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0629720&HistoricalAwards=false
• 关键词: US; Africa; Advanced; Studies; Institute

This award funds an Advanced Studies Institute on Mathematical Modeling of Infectious Disease in Africa, to be held in Cape Town, South Africa in June, 2007. In recent years, mathematical modeling of infectious diseases has had an increasing influence on the theory and practice of disease management with such diseases as HIV/AIDS, foot-and-mouth disease, and SARS, and this is increasingly the case with diseases of Africa. In order to further understand and prevent the spread of infectious diseases, it is vitally important to train young mathematicians and scientists who are both knowledgeable about modeling as well as about disease contexts and data gathering. The success of recent joint US-African modeling studies points to the advantages of such collaborations and to the need for more trained researchers and students from both sides. To address the issue of training, the Center for Discrete Mathematics and Theoretical Computer Science (DIMACS), in collaboration with the South African DST/NRF Centre of Excellence in Epidemiological Modeling and Analysis (SACEMA) and the African Institute for Mathematical Sciences (AIMS), will hold a two-week advanced studies institute in Cape Town, culminating in a 3-day "capstone" workshop at which institute students and researchers from both the US and Africa will interact and establish collaborations. The institute will emphasize mathematical techniques used in epidemiological modeling including advanced topics such as meta-population modeling, continuous vs. discrete-time stochastic models; models with vertical transmission; spatial and individual-based models; age structure; and optimal allocation of disease control resources such as vaccine and antiviral doses. The workshop will discuss the design of cost-effective, sustainable strategies for combating disease spread in Africa, including modern statistical tools for surveillance, network methods, and evolutionary aspects of diseases of humans and animals. Speakers will address mathematical modeling tools for dealing with shortages of resources, drug resistance to tuberculosis, challenges from HIV and malaria, and potential alternative interventions for pandemic flu. Materials arising from the institute will be widely disseminated so that others can use them. The project will help the DIMACS program bring current international research into the undergraduate classroom in the US. Partnering with four historically Black colleges and universities (Clark Atlanta, Howard, Morgan State, and North Carolina A&T) will enable a diverse group of students to participate in the institute. The institute will provide US students with advanced disease-modeling knowledge within an international context, open new lines of communication between US students and researchers and their African counterparts, and provide a solid basis for collaborative partnerships that can last well into the future. Finally, including such a wide range of factors in the course increases the likelihood that the students and researchers will generate new approaches to modeling disease epidemics such as HIV/AIDS in Africa and the rest of the world.This award is co-funded by the Division of Mathematical Sciences and the Division of Information and Intelligent Systems.

该奖项资助将于2007年6月在南非开普敦举行的非洲传染病数学建模高级研究所。近年来，传染病的数学建模对疾病管理的理论和实践产生了越来越大的影响，如艾滋病毒/艾滋病，口蹄疫和SARS，非洲疾病的情况也越来越多。 为了进一步了解和预防传染病的传播，培养年轻的数学家和科学家至关重要，他们既了解建模，也了解疾病背景和数据收集。最近美国-非洲联合建模研究的成功表明了这种合作的优势，以及双方需要更多训练有素的研究人员和学生。为了解决培训问题，离散数学和理论计算机科学中心（DIMACS）将与南非DST/NRF流行病学建模和分析卓越中心（SACEMA）和非洲数学科学研究所（AIMS）合作，在开普敦举办为期两周的高级研究所，在为期3天的“顶点”研讨会上，来自美国和非洲的研究所学生和研究人员将进行互动并建立合作。该研究所将强调流行病学建模中使用的数学技术，包括高级主题，如元人群建模，连续与离散时间随机模型;垂直传播模型;基于空间和个人的模型;年龄结构;以及疾病控制资源的优化分配，如疫苗和抗病毒剂量。研讨会将讨论如何设计成本效益高、可持续的战略，以防止非洲的疾病传播，包括用于监测的现代统计工具、网络方法以及人类和动物疾病的演变方面。发言者将讨论数学建模工具，用于处理资源短缺，结核病耐药性，艾滋病毒和疟疾的挑战，以及大流行性流感的潜在替代干预措施。将广泛传播该研究所的材料，以便其他人能够使用。该项目将帮助DIMACS计划将当前的国际研究带入美国的本科课堂。与四所历史悠久的黑人学院和大学（克拉克亚特兰大，霍华德，摩根州立大学和北卡罗来纳州A T）合作，将使不同群体的学生参与该研究所。该研究所将在国际范围内为美国学生提供先进的疾病建模知识，在美国学生和研究人员与非洲同行之间开辟新的沟通渠道，并为未来的合作伙伴关系提供坚实的基础。最后，在课程中包括这样一个广泛的因素，增加了学生和研究人员将产生新的方法来建模疾病流行病，如艾滋病毒/艾滋病在非洲和世界其他地区的可能性。这个奖项是由数学科学部和信息和智能系统部共同资助。