CAREER: Spectroscopic and Electrochemical Studies of Nanoparticle Size, Shape, and Surface Chemistry

职业：纳米颗粒尺寸、形状和表面化学的光谱和电化学研究

• 批准号: 0645041
• 负责人: Christy Haynes
• 金额: $ 64.5万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0645041&HistoricalAwards=false
• 关键词: CAREER; Spectroscopic; Electrochemical; Studies; Nanoparticle

AbstractCHE-0645041Haynes/MinnesotaWith the support of the Analytical and Surface Chemistry Program, Professor Haynes and her colleagues in the Department of Chemistry at the University of Minnesota are examining the effects of nanoscale materials on the function of cellular machinery. The effects of nanoparticle size, shape, composition and surface chemistry on the function of model cellular systems are investigated using electrochemical and spectroscopic probes. Carbon fiber microelectrode amperometry, and calcium ion imaging of cell function will be used to assay cytotoxicity of the nanoparticle materials. This Career award integrates graduate training in the area of nanomaterials with emphasis on technical writing and presentation of scientific results. Using electrochemical and spectroscopic probes, Professor Haynes and her coworkers are examining the effects of noble metal and polymeric nanoparticles on the function of model cell lines. Uptake of these materials as a function of size, shape, composition and chemistry will be used to understand cytotoxicity of these materials. Growing applications of nanomaterials in consumer products and in the general environment indicate a need for a better understanding of the effects of these materials on cellular function. This Career award integrates training in technical writing and presentation with the research training of graduate students.

在分析和表面化学项目的支持下，明尼苏达大学化学系的Haynes教授和她的同事正在研究纳米材料对细胞机制功能的影响。利用电化学和光谱探针研究了纳米颗粒的大小、形状、组成和表面化学对模型细胞系统功能的影响。碳纤维微电极安培法和细胞功能钙离子成像将用于测定纳米颗粒材料的细胞毒性。该职业奖整合了纳米材料领域的研究生培训，重点是技术写作和科学成果的展示。利用电化学和光谱探针，海恩斯教授和她的同事们正在研究贵金属和聚合纳米颗粒对模型细胞系功能的影响。摄取这些材料的大小，形状，组成和化学的功能将用于了解这些材料的细胞毒性。纳米材料在消费品和一般环境中的应用日益增长，表明需要更好地了解这些材料对细胞功能的影响。该职业奖将技术写作和演讲培训与研究生的研究培训相结合。