CAREER: Water-Soluble Phosphine Ligands and Catalysis

职业：水溶性膦配体和催化

• 批准号: 0645365
• 负责人: Brian Frost
• 金额: $ 57.85万
• 依托单位: Board of Regents, NSHE, obo University of Nevada, Reno
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-01 至 2013-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0645365&HistoricalAwards=false
• 关键词: CAREER; Water; Soluble; Phosphine; Ligands

This CAREER award by the Inorganic, Bioinorganic and Organometallic Chemistry program supports the work of Professor Brian J. Frost at the University of Nevada, Reno to study the development of new chiral phosphine ligands and environmentally friendly catalysts. The project centers on the design and synthesis of novel water-soluble phosphine ligands and the development of catalytic reactions, such as hydrogenation and C-C coupling reactions, in aqueous and/or biphasic media. Water is expected to become increasingly important as a solvent in future industrial processes as it is environmentally friendly, inexpensive, nontoxic, and nonflammable, and thus, presents far-reaching health and safety benefits. This project may provide scientifically fundamental and industrially relevant advances in the field of aqueous-phase catalysis; such as the utilization of pH to modulate reactivity. The educational aspect of this proposal focuses on improvements in K-12 science education in the Washoe County School District of Nevada. This program will provide teacher workshops, and will send undergraduate students out into the classrooms during the academic year via the Science Partners Program. In addition to research activities, undergraduate andgraduate students involved in this project will have the opportunity to participate in the preparation and production of a chemistry demonstration show entitled, "It's not magic, it's SCIENCE!" performed for K-12 students in northern Nevada.

这个由无机，生物无机和有机化学计划颁发的职业奖支持内华达州大学里诺的Brian J. Frost教授的工作，以研究新的手性膦配体和环境友好型催化剂的开发。 该项目的重点是设计和合成新型水溶性膦配体，以及在水相和/或两相介质中开发催化反应，如氢化和C-C偶联反应。 预计水作为溶剂在未来的工业过程中将变得越来越重要，因为它是环境友好的，廉价的，无毒的，不易燃的，因此，具有深远的健康和安全效益。 该项目可能提供水相催化领域的科学基础和工业相关进展;例如利用pH调节反应性。 该提案的教育方面侧重于改善内华达州瓦肖县学区的K-12科学教育。 该计划将提供教师研讨会，并将通过科学合作伙伴计划在学年期间将本科生送到教室。 除了研究活动外，参与该项目的本科生和研究生将有机会参与化学演示节目的准备和制作，该节目名为“这不是魔术，这是科学! "在北方内华达州为K-12学生表演。