Experimental and Numerical Simulation of the Fate of Airborne Nanoparticles from a Leak in a Manufacturing Process to Assess Worker Exposure

对制造过程中泄漏造成的空气中纳米颗粒的命运进行实验和数值模拟，以评估工人的暴露情况

• 批准号: 0646236
• 负责人: David Y.H. Pui
• 金额: $ 40万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至 2010-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0646236&HistoricalAwards=false
• 关键词: Experimental; Numerical; Simulation; Fate; Airborne

0646236PuiThe toxicity of nanoparticles has received increased attention in the recent years. Toxicologists proposed to determine the total airborne nanoparticle surface area as a health relevant measure in order to assess worker exposure. If there is a leak in nanoparticle production equipment, nanoparticles can be emitted in large quantities. Between the leak and the point of human exposure they undergo physical or chemical reactions that can change the particle properties, including number and surface area concentrations, morphology, or chemical composition. In this project the PI proposes to measure the fate of nanoparticles, emitted through a leak in a nanoparticle production process into a workplace environment. Dr. Pui will particularly focus on changes of the nanoparticle surface area.

[6646236pui]纳米颗粒的毒性近年来受到越来越多的关注。毒理学家建议确定空气中纳米颗粒的总表面积，作为一项与健康相关的措施，以评估工人的暴露程度。如果纳米颗粒生产设备发生泄漏，纳米颗粒可能会大量排放。在泄漏点和人类暴露点之间，它们会发生物理或化学反应，从而改变颗粒的性质，包括数量和表面积浓度、形态或化学成分。在这个项目中，PI提议测量纳米颗粒的命运，通过纳米颗粒生产过程中的泄漏排放到工作环境中。裴博士将特别关注纳米颗粒表面积的变化。