Experimental and Numerical Simulation of the Fate of Airborne Nanoparticles from a Leak in a Manufacturing Process to Assess Worker Exposure

纳米颗粒的毒性近年来受到越来越多的关注。毒物学家建议确定空气中纳米颗粒的总表面积，作为与健康有关的措施，以评估工人的暴露情况。如果纳米颗粒生产设备出现泄漏，纳米颗粒可能会大量排放。在泄漏和人体接触点之间，它们会经历物理或化学反应，这些反应可能会改变颗粒的性质，包括数量和表面积浓度、形态或化学成分。在这个项目中，PI建议测量通过纳米颗粒生产过程中的泄漏排放到工作场所环境中的纳米颗粒的命运。贝博士将特别关注纳米颗粒表面积的变化。

0646236PuiThe toxicity of nanoparticles has received increased attention in the recent years. Toxicologists proposed to determine the total airborne nanoparticle surface area as a health relevant measure in order to assess worker exposure. If there is a leak in nanoparticle production equipment, nanoparticles can be emitted in large quantities. Between the leak and the point of human exposure they undergo physical or chemical reactions that can change the particle properties, including number and surface area concentrations, morphology, or chemical composition. In this project the PI proposes to measure the fate of nanoparticles, emitted through a leak in a nanoparticle production process into a workplace environment. Dr. Pui will particularly focus on changes of the nanoparticle surface area.