Nicotinic acetylcholine receptors as targets in inflammatory and neurodegenerative processes

预计这项研究将产生的国家/社区效益是经济和社会性质的。该项目采用的新方法来识别炎症途径和调节，有可能为设计新型肽/蛋白药物提供至关重要的信息。鉴于畅销的蛋白质类药物每年的销售额超过100亿美元，该提案有可能为澳大利亚带来非常显著的经济效益。此外，治疗炎症性疾病的新型药物将减少受影响的个人人数，从而减少与炎症性疾病有关的身体和精神压力，从而为澳大利亚带来社会效益。

The national/community benefits that are expected to arise from this research are economic and social in nature. The novel approach employed in this project to identify inflammatory pathways and regulation has the potential to provide information that is critical in the design of novel peptide/protein based drugs. With blockbuster protein-based drugs having sales in excess of $10 billion per annum this proposal has the potential for very significant economic benefits for Australia. Furthermore, novel therapeutic agents for inflammatory diseases would have social benefits for Australia by decreasing the number of individuals affected and thereby reducing the physical and emotional stress associated with inflammatory diseases.