SBIR Phase I: Fast Two-Color Heterodyne Non-Contact Scanning System for Mapping Optical Parameters of Human Eye

SBIR 第一阶段：用于绘制人眼光学参数的快速双色外差非接触扫描系统

• 批准号: 0810475
• 负责人: Filipp Ignatovich
• 金额: $ 9.99万
• 依托单位: Lumetrics, Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0810475&HistoricalAwards=false
• 关键词: SBIR; Phase; Fast; Two; Color

This Small Business Innovation Research Phase I project develops a high speed and high sensitivity system for measuring optical dimensions of human eye, such as the total axial length, corneal thickness and the location and thickness of the crystalline lens, in a non-contact manner using infrared light, invisible to the eye. This task is accomplished by improving the existing technique of time domain low-coherence interferometry. In the case of a live patient, which in general cannot be immobilized for steady measurements, speed and sensitivity of the measurements are especially important to achieve high accuracy and precision. The broader impacts of this research will benefit a large part of the population that suffers from cataract and other vision problems. The U.S. population of over 65 years old is expected to increase to over 70 million in 2030. Therefore, there is a dramatic need for tools to treat the wave of eye diseases and problems inherent to such population. Information on the structure of the eye is required in eye surgeries, including those that deal with replacing the crystalline lenses affected by cataract. The proposed research will result in an array of critical tools aimed at mapping out the eye, for medical research and for more successful treatment of eye diseases.

该小型企业创新研究第一阶段项目开发了一种高速、高灵敏度系统，用于使用肉眼不可见的红外光以非接触方式测量人眼的光学尺寸，例如总眼轴长度、角膜厚度以及晶状体的位置和厚度。该任务是通过改进现有的时域低相干干涉测量技术来完成的。对于活体患者来说，通常无法固定其进行稳定测量，因此测量的速度和灵敏度对于实现高精度和高精度尤为重要。这项研究的更广泛影响将使大部分患有白内障和其他视力问题的人群受益。到 2030 年，美国 65 岁以上的人口预计将增加到 7000 万以上。因此，迫切需要治疗眼病浪潮和此类人群固有问题的工具。眼科手术需要有关眼睛结构的信息，包括那些涉及更换受白内障影响的晶状体的手术。拟议的研究将产生一系列关键工具，旨在绘制眼睛图、用于医学研究和更成功地治疗眼部疾病。