SBIR Phase II: Fiber-optic System for Fast Non-contact Measurements of Optical Structure of Human eye

SBIR第二阶段：用于快速非接触式测量人眼光学结构的光纤系统

• 批准号: 0923963
• 负责人: Filipp Ignatovich
• 金额: $ 48.92万
• 依托单位: Lumetrics, Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0923963&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Fiber; optic

This Small Business Innovation Research (SBIR) Phase II project is aimed at developing a high speed and high sensitivity system for measuring optical dimensions of human eye, such as the total axial length, corneal thickness and the location and thickness of the crystalline lens, in a non-contact manner using infrared light, invisible to the eye. This task is accomplished by improving the existing technique of time domain low-coherence interferometry. In case of a live patient, who cannot be immobilized for steady measurements, speed and sensitivity of the measurements are especially important to achieve high accuracy and precision. The broader impacts of this research are aimed at benefiting large part of the population that suffers from cataract and other vision problems. The U.S. population of over 65 years old expected to increase to over 70 million in 2030. Therefore, there is a dramatic need for tools to treat the wave of eye diseases and problems inherent to such population. Information on the structure of the eye is required in eye surgeries, including those that deal with replacing the crystalline lenses affected by cataract. The proposed research will result in an array of critical tools aimed at mapping out the eye, for medical research and for treatment of the diseases.

该小型企业创新研究（SBIR）第二阶段项目旨在开发一种高速和高灵敏度的系统，用于以非接触方式使用肉眼不可见的红外光测量人眼的光学尺寸，例如总眼轴长度，角膜厚度和晶体透镜的位置和厚度。这一任务是通过改进现有的时域低相干干涉测量技术来完成的。在不能固定住进行稳定测量的活体患者的情况下，测量的速度和灵敏度对于实现高准确度和精度尤其重要。这项研究的更广泛影响旨在使大部分患有白内障和其他视力问题的人口受益。美国65岁以上的人口预计将在2030年增加到7000多万。因此，迫切需要一种工具来治疗这一波眼部疾病和这类人群固有的问题。在眼科手术中，需要有关眼睛结构的信息，包括那些涉及更换受白内障影响的晶状体的手术。拟议中的研究将产生一系列关键工具，旨在绘制眼睛，用于医学研究和疾病治疗。