MRI: Acquisition of a Gemini R Ultra X-ray Diffractometer for Structural Biology and Chemistry

获得这项来自主要研究仪器计划（MRI）的奖项，罗杰·罗莱特和他的同事安东尼·奇尼斯和G。来自高露洁大学的Richard Geier III将获得一台单晶X射线衍射仪（XRD），以支持化学和生物化学研究，包括酶机制和结构、有机金属催化、卟啉大环化合物的研究以及大肠杆菌中细菌碳酸酐酶机制的研究。杆菌该仪器还将影响高露洁和地区本科院校的本科研究、培训和教学。单晶X射线晶体学技术允许准确和精确地确定分子的完整三维结构，包括键距和角度，并且它提供关于分子相对于相邻分子的空间排列的准确信息。这些研究将对从合成化学到生物学系统的许多领域产生影响。

With this award from the Major Research Instrumentation program (MRI), Roger Rowlett and colleagues Anthony Chianese and G. Richard Geier III from Colgate University will acquire a single-crystal X-ray diffractometer (XRD) to support research in chemistry and biochemistry including the study of enzyme mechanisms and structure, organometallic catalysis, porphyrinic macrocycles as well as examination of the mechanism of bacterial carbonic anhydrase in E. coli. The instrumentation will also impact undergraduate research, training, and teaching at Colgate and regional undergraduate institutions. The technique of single-crystal X-ray crystallography allows accurate and precise determination of the full three dimensional structure of a molecule, including bond distances and angles, and it provides accurate information about the spatial arrangement of molecules relative to the neighboring molecules. These studies will have an impact in a number of areas ranging from synthetic chemistry to systems of biological interest.