Computing in Life Sciences Through Hands-on Experience and Case Studies at Tuskegee University
通过塔斯基吉大学的实践经验和案例研究进行生命科学计算
基本信息
- 批准号:0837075
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-01-01 至 2010-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Biology has changed from an insular entity into a science dependant upon interdisciplinary and cross-disciplinary approaches. At the Tuskegee University (TU) and many institutions of higher education integration of bioinformatics and computational skills into the biology undergraduate curricula is an enterprise still in its infancy. This project advances that enterprise through development of a two-course sequence and five modules on bioinformatics and computing. These emphasize computational thinking and skills, provide students with hands-on experiences and a collaborative learning environment based on case studies and team projects, and rely on new learning enhancement software tools, instructional materials and lab manuals developed specifically for this project. Case study examples include identifying the alleles and paralogs of disease resistance genes in the sweet potato genome and mutation probablility and frequency during aging in the yeast.Intellectual Merit: The intellectual merit of this project lies in its initiative to develop materials and methods for teaching computational thinking to students in life sciences, its effort to develop comprehensive computer laboratory exercises that offer hands-on learning experience for the targeted student pool, and a case-study course design that challenges students to solve interesting problems in a collaborative learning environment. The project is designed to: promote excitement about computing in the minds of students in the life sciences; lead to student growth through interdisciplinary and cross-disciplinary experiences; encourage students to apply computation in their individual research projects; and cultivate student interest in pursuing research careers. Broader Impacts: The newly developed modules, instructional materials and educational software tools are impacting more than 100 students per year at TU, a historically black college. The courses developed are being offered as science electives to students in the Department of Computer Science and to bioinformatics concentrators in the Department of Chemistry. The broader impacts of this project include student experiences, curricula improvement, faculty development, and the potential for adoption and adaptation by other institutions of the material and the way it is being integrated into courses. The activities are also increasing faculty collaboration among the departments of Biology, Computer Science, Chemistry, and Agricultural and Environmental Sciences. In addition, the modular nature of the developed teaching materials is facilitating their dissemination outside of TU, thus enhancing the curricula at other institutions. The reliance on R, an open-source cross-platform computing environment, and other open-source software is contributing to the broader impacts of this project. Dissemination of the generated teaching materials is being facilitated by a dedicated website http://bioinformatics.org/ctls/ (Computational Thinking in Life Sciences), developed and maintained by the PI.
生物学已经从一个孤立的实体变成了一门依赖于跨学科和跨学科方法的科学。在塔斯基吉大学(TU)和许多高等教育机构,将生物信息学和计算技能整合到生物学本科课程中是一项仍处于起步阶段的事业。该项目通过开发关于生物信息学和计算的两门课程和五个模块来推进这项事业。这些强调计算思维和技能,为学生提供实践经验和基于案例研究和团队项目的协作学习环境,并依赖于专门为此项目开发的新的学习增强软件工具,教学材料和实验室手册。案例研究的例子包括鉴定甘薯基因组中抗病基因的等位基因和旁系同源基因,以及酵母老化过程中的突变概率和频率。该项目的智力价值在于它主动开发材料和方法,用于向生命科学学生教授计算思维,它努力开发全面的计算机实验室练习,为目标学生提供实践学习经验,和案例研究课程设计,挑战学生在协作学习环境中解决有趣的问题。该项目旨在:促进生命科学学生对计算的兴趣;通过跨学科和跨学科的经验引导学生成长;鼓励学生在个人研究项目中应用计算;以及培养学生从事研究事业的兴趣。 更广泛的影响:新开发的模块,教学材料和教育软件工具每年影响TU的100多名学生,TU是一所历史悠久的黑人大学。 开发的课程正在提供作为科学选修课的学生在计算机科学系和生物信息学集中在化学系。这个项目的更广泛的影响包括学生的经验,课程的改进,教师的发展,以及其他机构采用和改编材料的可能性,以及将其纳入课程的方式。这些活动也增加了生物学,计算机科学,化学,农业和环境科学部门之间的教师合作。此外,开发的教学材料的模块化的性质是促进他们的TU以外的传播,从而加强在其他机构的课程。对开源跨平台计算环境R和其他开源软件的依赖有助于该项目产生更广泛的影响。由PI开发和维护的专门网站http://bioinformatics.org/ctls/(生命科学中的计算思维)正在促进所生成的教学材料的传播。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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John Davidson其他文献
Triploidy in emMytilus edulis/em impacts the mechanical properties of byssal threads
欧洲贻贝三倍体影响了足丝的机械性能
- DOI:
10.1016/j.aquaculture.2022.739191 - 发表时间:
2023-03-15 - 期刊:
- 影响因子:3.900
- 作者:
Kevin Osterheld;John Davidson;Luc A. Comeau;Tiago Hori;José M.F. Babarro;Isabelle Marcotte;Christian Pellerin;Réjean Tremblay - 通讯作者:
Réjean Tremblay
Low head oxygenator performance characterization for marine recirculating aquaculture systems
- DOI:
10.1016/j.aquaeng.2016.10.001 - 发表时间:
2016-11-01 - 期刊:
- 影响因子:
- 作者:
Brian J. Vinci;John Davidson;Eyal Naveh;Or Engler - 通讯作者:
Or Engler
Assessment of the comparative agreement between chest radiographs and CT scans in intensive care units.
评估重症监护室胸部 X 光片和 CT 扫描之间的比较一致性。
- DOI:
10.1016/j.jcrc.2024.154760 - 发表时间:
2024 - 期刊:
- 影响因子:3.7
- 作者:
Daniel Brooks;Stephen E. Wright;Anna Beattie;Nadia McAllister;Niall H. Anderson;Alistair I. Roy;Philip Gonsalves;Bryan Yates;S. Graziadio;Alasdair Mackie;John Davidson;Sandeep Vijaya Gopal;Robert Whittle;Asef Zahed;Lorna Barton;Mathew Elameer;J. Tuckett;Rob Holmes;Alexandra Sutcliffe;Nuria Santamaria;Luke la Hausse de Lalouviere;Sanjay Gupta;Jeevan Subramaniam;Janaki A. Pearson;Matthew Brandwood;Richard Burnham;A. Rostron;A. J. Simpson - 通讯作者:
A. J. Simpson
The effects of two water temperature regimes on Atlantic salmon (<em>Salmo salar</em>) growth performance and maturation in freshwater recirculating aquaculture systems
- DOI:
10.1016/j.aquaculture.2022.738063 - 发表时间:
2022-05-15 - 期刊:
- 影响因子:
- 作者:
Curtis Crouse;John Davidson;Christopher Good - 通讯作者:
Christopher Good
Performance, processing yields, and fillet composition of specific United States diploid and triploid rainbow trout (emOncorhynchus mykiss/em) lines reared in a semi-commercial scale freshwater recirculating aquaculture system
在美国半商业化规模的淡水循环水产养殖系统中养殖的特定美国二倍体和三倍体虹鳟(Oncorhynchus mykiss)品系的性能、加工产量和鱼片成分
- DOI:
10.1016/j.aqrep.2023.101794 - 发表时间:
2023-12-01 - 期刊:
- 影响因子:3.700
- 作者:
Curtis Crouse;Anna Knight;Travis May;John Davidson;Christopher Good - 通讯作者:
Christopher Good
John Davidson的其他文献
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{{ truncateString('John Davidson', 18)}}的其他基金
Implementation Grant: Development of Multidepartmental, Multidisciplinary Concentrations at Tuskegee University
实施补助金:塔斯基吉大学多部门、多学科专业的发展
- 批准号:
0938273 - 财政年份:2009
- 资助金额:
-- - 项目类别:
Continuing Grant
Civil Engineering Research Equipment: A Mobile 20-Ton Cone Penetration System for In situ Soil Testing
土木工程研究设备:用于原位土壤测试的移动式 20 吨圆锥贯入系统
- 批准号:
8406211 - 财政年份:1984
- 资助金额:
-- - 项目类别:
Standard Grant
The Quasi-Preconsolidation Effect in Clays and Its Role in Soil-Structure Interaction
粘土中的准预固结效应及其在土-结构相互作用中的作用
- 批准号:
8116906 - 财政年份:1982
- 资助金额:
-- - 项目类别:
Continuing grant
The Effects of Hisu on Control of Macromolecular Synthesis
Hisu对大分子合成的控制作用
- 批准号:
8208510 - 财政年份:1982
- 资助金额:
-- - 项目类别:
Standard Grant
Doctoral Dissertation Research in Systematic Biology
系统生物学博士论文研究
- 批准号:
8105441 - 财政年份:1981
- 资助金额:
-- - 项目类别:
Standard Grant
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