The molecular anatomy of synaptic vesicle recycling at the hair cell ribbon synapse (A05+)
The molecular anatomy of synaptic vesicle recycling at the hair cell ribbon synapse (A05+)
批准号:
192923792
负责人:
金额:
$0.0万
依托单位国家:
德国
项目类别:
Collaborative Research Centres
财政年份:
2011
资助国家:
德国
项目状态:
已结题
起止时间:
2010-12-31 至 2018-12-31
中文摘要
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英文摘要
A05 proposes to use several molecular and metabolic imaging tools that we have recently developed, including nanoscale secondary ion mass spectrometry (nanoSIMS) and 10X expansion microscopy (X10), to measure protein turnover in inner hair cells (IHCs). This should enable us to suggest if sensory regimes promote IHC turnover and “rejuvenation”, which may have important consequences in hearing disorders linked to IHC degeneration.
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