SBIR Phase I: UltraWave: A Combined Breast Imaging Solution

SBIR 第一阶段：UltraWave：组合乳腺成像解决方案

• 批准号: 0912432
• 负责人: khaled salama
• 金额: $ 7.77万
• 依托单位: Parvulus Solutions inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0912432&HistoricalAwards=false
• 关键词: SBIR; Phase; UltraWave; Combined; Breast

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This Small Business Innovation Research Phase I research proposal is to experimentally verify the feasibility of combining ultrasound imaging and microwave imaging for the detection of malignant cells. This effort will investigate the feasibility of a novel medical imaging solution that provides high resolution images matching the quality of Magnetic Resonance Imaging (MRI) systems at the high throughput and low cost of X-ray systems. This involves coupling an ultrasound subsystem for exciting target tissues with a microwave subsystem for measuring the response and imaging the target tissues. The system combines the superior penetration and resolution characteristics of focused high-frequency ultrasound input waves, and the superior penetration and detection capacity of microwave detection and imaging.Breast cancer is among the most common forms of cancer for nonsmokers. Among the 1.2 million women diagnosed with breast cancer in 2005, 0.5 million died from the disease. Recent research studies at Sloan Kettering Hospital show that mammography detects only 50% of breast cancer cases at an early stage. Breast cancer has received a great deal of attention due to the inadequacy of existing screening technologies for early-stage detection. These recent findings emphasize the immense financial burden on patients and the medical community since MRI screenings cost about $1,500, i.e. nearly 10 times more than X-ray mammography. Consequently, there is a dire need for an imaging solution that matches the resolution and quality of MRI at the cost of X-ray mammography.

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。这项小企业创新研究第一阶段的研究提案是通过实验验证超声成像和微波成像相结合用于检测恶性细胞的可行性。这项工作将研究一种新型医学成像解决方案的可行性，该解决方案在X射线系统的高吞吐量和低成本下提供与磁共振成像（MRI）系统质量相匹配的高分辨率图像。这涉及将用于激励目标组织的超声子系统与用于测量响应并对目标组织成像的微波子系统耦合。该系统结合了聚焦高频超声输入波的上级穿透和分辨率特性，以及微波检测和成像的上级穿透和检测能力。乳腺癌是非吸烟者最常见的癌症之一。在2005年被诊断患有乳腺癌的120万妇女中，有50万人死于这种疾病。斯隆凯特琳医院最近的研究表明，乳房X光检查只能在早期阶段检测到50%的乳腺癌病例。由于现有的早期检测筛查技术的不足，乳腺癌受到了极大的关注。这些最近的发现强调了患者和医疗界的巨大经济负担，因为MRI筛查的费用约为1，500美元，即几乎是X射线乳房X光检查的10倍。因此，迫切需要一种成像解决方案，以X射线乳腺摄影为代价，与MRI的分辨率和质量相匹配。