Organization of the Telencephalon in Lungfishes

肺鱼端脑的组织

• 批准号: 0919077
• 负责人: R. Glenn Northcutt
• 金额: $ 30万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0919077&HistoricalAwards=false
• 关键词: Organization; Telencephalon; Lungfishes

"This award is funded under the American Recovery and Reinvestment Act of 2009(Public Law 111-5)."The principal investigator studies vertebrate brains and how they have evolved to subserve different behaviors and adaptations. In this project he will study the brain of the African lungfish, with various techniques that will reveal its structure and organization. We know that the animals that first emerged from the sea to live on land were lobe-finned fishes, but we know little else about these ancestors of all land vertebrates. Information on living lobe-finned fishes, however, will allow us to infer a great deal of information regarding the biology of this ancestor, particularly when that information is compared with data on amphibians, which descended from these early land-dwellers. Brain organization, particularly the organization of the forebrain, has been used to provide valuable clues to an animal's biology and it's taxonomic relationships with other animals. Little is known about brain organization in the living lobe-finned fishes, as they are few in number and have not been convenient to study. In addition to the infamous and elusive coelacanth, the living lobe-finned fishes are only six species of lungfishes, native to Africa, South America, and Australia. This project will generate such information and has the potential to provide valuable insight into the field of comparative neuroanatomy. The newly found information will be compared with existing information on amphibian brains to test the hypothesis that the brains of living lobe-finned fishes are far more like those of amphibians than has previously been believed. The similarities in brain organization between living lobe-finned fishes and amphibians likely existed also in their common ancestor, and thus will allow scientists to infer much needed information about the first land animals to emerge from the sea to live on land. This project will provide resources to continue dissemination of this work among scholars and the lay public across the world.

“该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。“首席研究员研究脊椎动物的大脑以及它们如何进化以满足不同的行为和适应。 在这个项目中，他将研究非洲肺鱼的大脑，用各种技术来揭示它的结构和组织。 我们知道，最早从海洋中出现并在陆地上生活的动物是圆鳍鱼，但我们对所有陆地脊椎动物的祖先知之甚少。 然而，关于现存的圆鳍鱼类的信息将使我们能够推断出大量关于这一祖先的生物学信息，特别是当这些信息与两栖动物的数据进行比较时，两栖动物是这些早期陆地居民的后裔。 脑组织，特别是前脑的组织，已被用来提供有价值的线索，动物的生物学和它的分类与其他动物的关系。 由于现存的长须鲸数量少，研究起来也不方便，因此对它们的脑组织知之甚少。 除了声名狼借和难以捉摸的腔棘鱼外，现存的叶鳍鱼只有六种肺鱼，原产于非洲，南美洲和澳大利亚。 这个项目将产生这样的信息，并有可能提供有价值的洞察比较神经解剖学领域。 新发现的信息将与两栖动物大脑的现有信息进行比较，以验证活的叶鳍鱼的大脑比以前认为的更像两栖动物的假设。 现存的圆鳍鱼类和两栖动物之间大脑组织的相似性可能也存在于它们的共同祖先中，因此将使科学家能够推断出有关第一批从海洋中出现并生活在陆地上的陆地动物的急需信息。 该项目将提供资源，继续在世界各地的学者和非专业公众中传播这项工作。