MRI: Acquisition of a Roche Genome Sequencer Titanium System for Studies of Microbial Communities

这项重大研究仪器(MRI)奖为收购罗氏基因组测序仪FLX钛系统提供资金，该系统可以在加州大学戴维斯分校进行大规模高通量的“下一代”DNA测序。该系统将构成微生物多样性测序设施的核心，该设施将成为加州大学戴维斯分校校园内微生物多样性研究和教育的活跃中心，并与外部合作者合作。微生物多样性是加州大学戴维斯分校许多关键研究领域的基础，包括农业、葡萄栽培、微生物学、进化论、生态学、生物能源、生物修复、营养和植物、动物和人类的发病机制。罗氏基因组测序仪FLX钛系统将在这些优势的基础上，通过彻底改变校园内数十个实验室的研究，促进研究人员之间的富有成效的互动，研究微生物群落的不同方面，并招募新的研究人员进入该领域。此外，该系统将通过加州大学戴维斯分校基因组中心的核心设施向校园和该地区的其他人提供。该系统将振兴和塑造多样化的教育、培训和外展活动。此外，微生物多样性测序设施将在培训本科生、研究生和博士后收集和有意义地使用大量DNA序列数据方面发挥作用。最后，该仪器将与外部本科教育机构合作使用，为他们提供设备和数据，这些数据可用作课程和研究活动的一部分。通过使用该设备产生的研究、教育和推广活动将在http://microbialdiversity.ucdavis.edu.的一个项目网站上总结

This Major Research Instrumentation (MRI) award funds the acquisition of a Roche Genome Sequencer FLX Titanium System that allows massively high throughput "Next Generation" DNA sequencing at the University of California (UC) Davis. This system will form the core of a Microbial Diversity Sequencing Facility that will serve as an active center for both research and education in microbial diversity across the UC Davis Campus and with outside collaborators. Microbial diversity is fundamental to many key fields of research at UC Davis including agriculture, viticulture, microbiology, evolution, ecology, bioenergy, bioremediation, nutrition, and pathogenesis in plants, animals, and humans. The Roche Genome Sequencer FLX Titanium System will build on these strengths by revolutionizing the research in dozens of labs across campus, facilitating productive interaction between researchers investigating different aspects of microbial communities, and recruiting new researchers to this field. In addition, the system will be made available to others on campus and in the area through a core facility in the UC Davis Genome Center. The system will invigorate and shape diverse educational, training, and outreach activities. Furthermore, the Microbial Diversity Sequencing Facility will function in training undergraduates, graduate students, and post-docs in the gathering and meaningful use of massive amounts of DNA sequence data. Finally, the instrumentation will be used in partnerships with outside undergraduate educational institutions to provide them with access both to the equipment and to data that can be used as part of courses and research activities.Research, educational and outreach activities produced through the use of this equipment will be summarized on a project web site at http://microbialdiversity.ucdavis.edu.