Mechanistic links between phytochrome signaling and chloroplast differentiation
光敏色素信号传导与叶绿体分化之间的机制联系
基本信息
- 批准号:0923722
- 负责人:
- 金额:$ 15万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-08-01 至 2011-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).PI: Meng Chen, Ph.D.Proposal Number: IOS-0923722Title: Mechanistic links between phytochrome signaling and chloroplast differentiationChloroplast differentiation, or how plants turn green after germination, is critical to the establishment of photosynthetic plastids that enable plant to undergo photosynthesis. Thus, it is an essential process during light-dependent plant development. Although it is well known that chloroplast differentiation is controlled mainly by the red and far-red photoreceptor phytochromes, little is known about the molecular mechanisms by which phytochromes initiate this process. Recently, the investigators identified a novel and essential component for phytochrome signaling, HEMERA (HMR), in the model plant species Arabidopsis. Interestingly, HMR is the first phytochrome signaling component discovered so far that is also required for chloroplast differentiation. HMR encodes a highly conserved protein in land plants, and was previously shown to be associated with plastidic transcriptional machinery. However, preliminary evidence from the investigators suggests that HMR should be localized in the nucleus. The research undertaken as part of this project aims to solve this dilemma, by determining the subcellular localization of HMR and to define its localization signals using a combination of genetics, biochemical, and cell biological approaches. The proposed research is likely to unravel novel mechanisms linking phytochrome signaling and the initiation of chloroplast differentiation. The elucidation of molecular mechanisms for chloroplast differentiation will contribute significantly to our basic knowledge of how nuclear and organellar genomes coordinate their responses to environmental cues, and will also have deep implications in improving yield in agriculture. In addition, the proposed projects will provide excellent training in molecular genetic approaches for postdoctoral fellows, graduate students, and undergraduate students.
该奖项是根据2009年美国复苏和再投资法案(公法111-5)资助的。PI:Meng Chen,Ph.D.Proposal Number:IOS-0923722 Title:Mechanism links between phytochrome signaling and chloroplast differentiation叶绿体分化,或植物如何在发芽后变绿色,对于建立光合质体使植物进行光合作用至关重要。 因此,它是光依赖植物发育过程中的一个重要过程。 虽然众所周知,叶绿体分化主要是由红色和远红色光感受器光敏色素控制,但对光敏色素启动这一过程的分子机制知之甚少。最近,研究人员在模式植物拟南芥中发现了光敏色素信号传导的一种新的重要成分HEMERA(HMR)。 有趣的是,HMR是迄今为止发现的第一个光敏色素信号组分,也是叶绿体分化所需的。HMR在陆地植物中编码高度保守的蛋白质,并且先前被证明与质体转录机制相关。 然而,研究人员的初步证据表明,HMR应该定位于细胞核。 作为该项目的一部分进行的研究旨在解决这一困境,通过确定HMR的亚细胞定位,并使用遗传学,生物化学和细胞生物学方法的组合来定义其定位信号。 这项研究有望揭示光敏色素信号传导与叶绿体分化启动之间的新机制。 叶绿体分化的分子机制的阐明将有助于我们的核和细胞器基因组如何协调其响应环境线索的基础知识,也将在提高农业产量的深刻影响。 此外,拟议的项目将提供优秀的培训,在分子遗传学的方法,博士后研究员,研究生和本科生。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Meng Chen其他文献
Comprehensive investigation of mechanism and effective ingredients of Fangji Huangqi Tang by serum pharmacochemistry and network pharmacology
血清药物化学和网络药理学综合研究防己黄芪汤的作用机制和有效成分
- DOI:
10.1002/bmc.4785 - 发表时间:
2019 - 期刊:
- 影响因子:1.8
- 作者:
Liu Yang;Aiping Li;Meng Chen;Yan Yan;Yuetao Liu;Ke Li;Jinping Jia;Xuemei Qin - 通讯作者:
Xuemei Qin
Preparation, characterization and electrochemistry of viologen-functionalized carbon nanotubes in the casting films and layer-by-layer multilayers
流延膜和逐层多层膜中紫罗碱功能化碳纳米管的制备、表征和电化学
- DOI:
10.1016/j.colsurfa.2013.08.037 - 发表时间:
2013-09 - 期刊:
- 影响因子:0
- 作者:
Jiang Liu;Meng Chen;Dong-Jin Qian - 通讯作者:
Dong-Jin Qian
Elevated lactate levels in a non-critically ill patient.
非危重患者的乳酸水平升高。
- DOI:
- 发表时间:
2015 - 期刊:
- 影响因子:0
- 作者:
Meng Chen;Tiffany Y Kim;Antonio M. Pessegueiro - 通讯作者:
Antonio M. Pessegueiro
Electrochemical properties of hydrogenase on glass carbon electrodes modified with carbon nanotubes
碳纳米管修饰玻碳电极上氢化酶的电化学性能
- DOI:
- 发表时间:
2006 - 期刊:
- 影响因子:0
- 作者:
Ai;D. Qian;Meng Chen;T. Wakayama;C. Nakamura;N. Zorin;J. Miyake - 通讯作者:
J. Miyake
Embedding Hierarchical Structures for Venue Category Representation
嵌入用于场地类别表示的层次结构
- DOI:
10.1145/3478285 - 发表时间:
2021-11 - 期刊:
- 影响因子:5.6
- 作者:
Meng Chen;Lei Zhu;Ronghui Xu;Yang Liu;Xiaohui Yu;Yilong Yin - 通讯作者:
Yilong Yin
Meng Chen的其他文献
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{{ truncateString('Meng Chen', 18)}}的其他基金
Perinuclear Positioning of Active Genes in Arabidopsis
拟南芥中活性基因的核周定位
- 批准号:
2141560 - 财政年份:2022
- 资助金额:
$ 15万 - 项目类别:
Standard Grant
EAGER: spRNA-seq: high-throughput transcriptome analysis of single plastids
EAGER:spRNA-seq:单个质体的高通量转录组分析
- 批准号:
2034015 - 财政年份:2020
- 资助金额:
$ 15万 - 项目类别:
Standard Grant
Uncovering HEMERA-mediated Phytochrome Signaling Mechanisms in Arabidopsis
揭示拟南芥中 HEMERA 介导的光敏色素信号机制
- 批准号:
1051602 - 财政年份:2011
- 资助金额:
$ 15万 - 项目类别:
Continuing Grant
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