EAGER: Collaborative Research: Integration of the Capillary Waveguide Biosensor (CWB) with the Environmental Sample Processor (ESP): Detection of microorga

EAGER：合作研究：毛细管波导生物传感器 (CWB) 与环境样品处理器 (ESP) 的集成：微生物检测

• 批准号: 0929238
• 负责人: Josephine Aller
• 金额: $ 21.39万
• 依托单位: SUNY at Stony Brook
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0929238&HistoricalAwards=false
• 关键词: EAGER; Collaborative; Research; Integration; Capillary

The PI's request EAGER funding to focus on validation of the coupled CWB-ESP instrument using field collected materials. This will not only allow the PI?s to overcome reviewer concerns, but will be a major step forward in preparing the CWB-ESP system for routine field deployment. The main objectives include:1: Coupling the CWB to the ESP: the Microfluidic Block (MFB) interface2: Select and optimize hybridization and detection protocols3: Detection of targets in field-collected samples using model systemsBroader ImpactsThe proposed ESP-integrated CWB is potentially a major advance toward unattended, long term study of specific populations of the microbial community, with numerous potential applications beyond ecological research. During the course of this research, graduate, undergraduate and high school students will be involved directly and trained in the fundamentals of design and analysis of systems. The PI's intend to engage diverse students and underserved minorities, by incorporating their research ideas and work into existing educational programs.

国际和平研究所迫切要求提供资金，以便利用实地收集的材料对CWB-ESP耦合仪器进行验证。这不仅将使皮？S克服审查员的担忧，而且将是为常规现场部署准备CWB-ESP系统的重要一步。主要目标包括：1：将CWB连接到ESP：微流控模块(MFB)接口2：选择和优化杂交和检测协议3：使用模型系统检测现场采集样本中的目标布罗德影响拟议的集成ESP的CWB可能是朝着无人值守的、长期的微生物群落特定种群研究的重大进展，除了生态学研究外，还有许多潜在的应用。在这项研究的过程中，研究生、本科生和高中生将直接参与，并接受系统设计和分析基础知识的培训。PI‘s打算通过将他们的研究想法和工作纳入现有的教育计划，吸引不同的学生和服务不足的少数族裔。