Electrical Detection of Protein Binding at DNA Modified Carbon Nanotube Field Effect Transistors

该奖项是根据2009年美国复苏和再投资法案(公法111-5)资助的。化学部支持哥伦比亚大学的阿隆·戈罗德斯基作为美国化学竞争力研究员。戈罗德斯基博士将开发用于场效应晶体管的化学修饰碳纳米管(带有DNA)。将评估这些分子电子设备对检测少量蛋白质的适用性。戈罗代茨基博士将与哥伦比亚大学的科学家合作开展实验工作，并将与布鲁克海文国家实验室的理论家合作。为了扩大参与范围，戈罗德斯基博士将从耶希瓦大学斯特恩学院招募和指导女性化学家，研究将在哥伦比亚大学科林·纳科尔斯教授的实验室进行。像戈罗德斯基博士这样的研究旨在开发新的生物分子传感器。这类研究的最终目标是开发改进的方法来快速检测重要的生物分子(例如癌症生物标记物)，以帮助研究人员和临床医生快速而廉价地进行测量。戈罗代茨基博士正在进行的扩大参与的努力旨在增加来自代表性不足群体的年轻人对科学的参与。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The Division of Chemistry supports Alon Gorodetsky of Columbia University as an American Competitiveness in Chemistry Fellow. Dr. Gorodetsky will develop chemically modified carbon nanotubes (with attached DNA) to be used in field effect transistors. The suitability of these molecular electronic devices to detect small quantities of proteins will be assessed. Dr. Gorodetsky will conduct experimental work in collaboration with scientists at Columbia University, and will work with theorists at Brookhaven National Laboratory. For his plan for broadening participation, Dr. Gorodetsky will recruit and mentor women chemists from Stern College, Yeshiva University in research to be conducted in the laboratories of Prof. Colin Nuckolls at Columbia University.Research like that of Dr. Gorodetsky is aimed at developing new sensors for biological molecules. The ultimate goal of research like this is to develop improved methods for the rapid detection of important biological molecules (e.g. cancer biomarkers) to aid researchers and clinicians in making measurements quickly and inexpensively. The efforts at broadening participation being pursued by Dr. Gorodetsky are aimed at increasing the participation of young people from underrepresented groups in the sciences.