Electrical Detection of Protein Binding at DNA Modified Carbon Nanotube Field Effect Transistors

该奖项由 2009 年美国复苏和再投资法案（公法 111-5）资助。化学部支持哥伦比亚大学的 Alon Gorodetsky 作为美国化学竞争力研究员。 Gorodetsky 博士将开发用于场效应晶体管的化学改性碳纳米管（带有 DNA）。 将评估这些分子电子设备检测少量蛋白质的适用性。 戈罗德茨基博士将与哥伦比亚大学的科学家合作进行实验工作，并将与布鲁克海文国家实验室的理论家合作。 为了扩大参与范围，戈罗德茨基博士将招募并指导叶史瓦大学斯特恩学院的女化学家，在哥伦比亚大学科林·纳科尔斯教授的实验室进行研究。戈罗德茨基博士的研究旨在开发用于生物分子的新型传感器。 此类研究的最终目标是开发快速检测重要生物分子（例如癌症生物标志物）的改进方法，以帮助研究人员和临床医生快速且廉价地进行测量。 戈罗德茨基博士正在努力扩大参与范围，旨在增加科学领域代表性不足群体的年轻人的参与。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).The Division of Chemistry supports Alon Gorodetsky of Columbia University as an American Competitiveness in Chemistry Fellow. Dr. Gorodetsky will develop chemically modified carbon nanotubes (with attached DNA) to be used in field effect transistors. The suitability of these molecular electronic devices to detect small quantities of proteins will be assessed. Dr. Gorodetsky will conduct experimental work in collaboration with scientists at Columbia University, and will work with theorists at Brookhaven National Laboratory. For his plan for broadening participation, Dr. Gorodetsky will recruit and mentor women chemists from Stern College, Yeshiva University in research to be conducted in the laboratories of Prof. Colin Nuckolls at Columbia University.Research like that of Dr. Gorodetsky is aimed at developing new sensors for biological molecules. The ultimate goal of research like this is to develop improved methods for the rapid detection of important biological molecules (e.g. cancer biomarkers) to aid researchers and clinicians in making measurements quickly and inexpensively. The efforts at broadening participation being pursued by Dr. Gorodetsky are aimed at increasing the participation of young people from underrepresented groups in the sciences.