2010 Auditory System and GRS Conference, Symposia & Workshops -Auditory System @ Colby-Sawyer College 6-13-18-2010 & Second Graduate Research Seminar 6-12-13-2010 in New Lo
2010 Auditory System and GRS Conference, Symposia & Workshops -Auditory System @ Colby-Sawyer College 6-13-18-2010 & Second Graduate Research Seminar 6-12-13-2010 in New Lo
批准号:
0940875
负责人:
Lisa Goodrich
金额:
$1.5万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-01-15 至 2010-12-31
中文摘要
听到和理解复杂声音刺激的能力取决于精确组织的神经元网络,这些神经元具有特殊的特性,能够快速检测和感知声音,并在广泛的强度和频率范围内。听力始于内耳中的机械敏感毛细胞对声音的检测。这些信息被编码并通过螺旋神经节忠实地传递到中枢神经系统。随后,一系列的处理事件在听觉脑干中并行发生,在下丘再次聚合。下丘投射到听觉丘脑和听觉皮层,听觉皮层是声音感知的所在地。大多数听觉研究小组专注于听觉处理的离散元素,如毛细胞功能或听觉神经元的电生理特性。然而,声音的感知最终是所有这些独立事件的产物,其中许多事件相互影响。听觉回路任何一个层面的故障都会对整个系统产生影响,特别是在发育过程中,可塑性机制会导致线路的永久性变化。这些问题的研究是第二届两年一度的戈登研究会议的目标听觉系统,这将发生在科尔比-索耶学院从2010年6月13日至18日,并将由第二次相关的研究生研究研讨会在2010年6月12日至13日之前。 该奖项为研究生和博士后研究员参加这些活动提供支持,这将提供丰富的培训环境,并促进各级听觉电路组装和功能的理解。
英文摘要
The ability to hear and understand complex sound stimuli depends on precisely organized networks of neurons with specialized properties that enable detection and perception of sounds quickly and over a wide range of intensities and frequencies. Hearing begins with the detection of sound by mechanosensitive hair cells in the inner ear. This information is encoded and faithfully transmitted to the central nervous system by the spiral ganglion. Subsequently, a series of processing events occur in parallel in the auditory brainstem, converging once again in the inferior colliculus. The inferior colliculus projects to the auditory thalamus and on to the auditory cortex, which is the seat of sound perception. Most auditory research groups focus on discrete elements of auditory processing, such as hair cell function or the electrophysiological properties of auditory neurons. However, the perception of sound is ultimately a product of all of these independent events, many of which influence each other. A failure at any level of the auditory circuitry has ramifications for the entire system, especially during development when mechanisms of plasticity can induce permanent changes in wiring. The study of these issues is the goal of the second biennial Gordon Research Conference on The Auditory System, which will take place at Colby-Sawyer College from June 13-18, 2010 and will be preceded by the second associated Graduate Research Seminar on June 12-13, 2010. This award provides support for graduate students and postdoctoral fellows to attend these events, which will provide a rich training environment and advance the understanding of auditory circuit assembly and function at all levels.
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