2010 Auditory System and GRS Conference, Symposia & Workshops -Auditory System @ Colby-Sawyer College 6-13-18-2010 & Second Graduate Research Seminar 6-12-13-2010 in New Lo

2010年听觉系统和GRS会议、研讨会

基本信息

  • 批准号:
    0940875
  • 负责人:
  • 金额:
    $ 1.5万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2010
  • 资助国家:
    美国
  • 起止时间:
    2010-01-15 至 2010-12-31
  • 项目状态:
    已结题

项目摘要

The ability to hear and understand complex sound stimuli depends on precisely organized networks of neurons with specialized properties that enable detection and perception of sounds quickly and over a wide range of intensities and frequencies. Hearing begins with the detection of sound by mechanosensitive hair cells in the inner ear. This information is encoded and faithfully transmitted to the central nervous system by the spiral ganglion. Subsequently, a series of processing events occur in parallel in the auditory brainstem, converging once again in the inferior colliculus. The inferior colliculus projects to the auditory thalamus and on to the auditory cortex, which is the seat of sound perception. Most auditory research groups focus on discrete elements of auditory processing, such as hair cell function or the electrophysiological properties of auditory neurons. However, the perception of sound is ultimately a product of all of these independent events, many of which influence each other. A failure at any level of the auditory circuitry has ramifications for the entire system, especially during development when mechanisms of plasticity can induce permanent changes in wiring. The study of these issues is the goal of the second biennial Gordon Research Conference on The Auditory System, which will take place at Colby-Sawyer College from June 13-18, 2010 and will be preceded by the second associated Graduate Research Seminar on June 12-13, 2010. This award provides support for graduate students and postdoctoral fellows to attend these events, which will provide a rich training environment and advance the understanding of auditory circuit assembly and function at all levels.
听到和理解复杂声音刺激的能力依赖于精确组织的神经元网络,这些神经元具有特殊的特性,能够快速地探测和感知各种强度和频率的声音。听力开始于内耳的机械敏感毛细胞对声音的探测。这些信息被编码并通过螺旋神经节忠实地传递到中枢神经系统。随后,一系列处理事件在听觉脑干平行发生,再次在下丘汇合。下丘投射到听觉丘脑和听觉皮层,听觉皮层是声音感知的所在地。大多数听觉研究小组专注于听觉处理的离散元素,如毛细胞功能或听觉神经元的电生理特性。然而,声音的感知最终是所有这些独立事件的产物,其中许多事件相互影响。听觉回路的任何级别的故障都会对整个系统产生影响,特别是在发育过程中,可塑性机制会导致线路的永久性变化。对这些问题的研究是第二届两年一次的戈登听觉系统研究会议的目标,该会议将于2010年6月13日至18日在科尔比-索耶学院举行,在此之前,第二届相关的研究生研究研讨会将于2010年6月12日至13日举行。该奖项为研究生和博士后参加这些活动提供了支持,这将提供丰富的培训环境,并在各个层面上促进对听觉回路组装和功能的理解。

项目成果

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Lisa Goodrich其他文献

Axon branching in spiral ganglion neurons
  • DOI:
    10.1016/j.ydbio.2008.05.127
  • 发表时间:
    2008-07-15
  • 期刊:
  • 影响因子:
  • 作者:
    Cindy Lu;Jesse Appler;Lisa Goodrich
  • 通讯作者:
    Lisa Goodrich
Deaf and dizzy mice: A genetic dissection of inner ear development
  • DOI:
    10.1016/j.ydbio.2009.05.085
  • 发表时间:
    2009-07-15
  • 期刊:
  • 影响因子:
  • 作者:
    Lisa Goodrich;Victoria Abraira;Tony Del Rio;Sayeeda Ahsanuddin
  • 通讯作者:
    Sayeeda Ahsanuddin
Combinatorial transcriptional regulation establishes subtype-appropriate synaptic properties in auditory neurons
组合式转录调控在听觉神经元中建立了适合亚型的突触特性
  • DOI:
    10.1016/j.celrep.2025.115796
  • 发表时间:
    2025-06-24
  • 期刊:
  • 影响因子:
    6.900
  • 作者:
    Isle Bastille;Lucy Lee;Cynthia Moncada-Reid;Wei-Ming Yu;Austen Sitko;Andrea Yung;Mina Zamani;Nele Christophersen;Reza Maroofian;Hamid Galehdari;Norbert Babai;Barbara Vona;Tobias Moser;Lisa Goodrich
  • 通讯作者:
    Lisa Goodrich
Imaging and analysis of interactions between individually labeled spiral ganglion neurons and hair cells in the developing mammalian cochlea
  • DOI:
    10.1016/j.ydbio.2011.05.280
  • 发表时间:
    2011-08-01
  • 期刊:
  • 影响因子:
  • 作者:
    Thomas Coate;Lisa Goodrich;Matthew Kelley
  • 通讯作者:
    Matthew Kelley

Lisa Goodrich的其他文献

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