Developmental and Evolutionary Regulation of Fish Body Shape, Conference Grant- the Society for Integrative and Comparative Biology annual meeting in Seattle WA, Jan. 4-7 2010

PI：Jeffrey A. Walker提案编号：0949102提案标题：鱼体形的发育和进化调节当前和未来生物学研究的一个主要方向是了解多个相互作用的功能系统如何协调产生一个工作的身体。这种理解是复杂的，因为生物体需要在多种环境中良好地工作，既有可预测的，也有不可预测的环境扰动。此外，有机体设计反映了过去环境的历史，而不是未来环境的计划。因此，复杂的、相互作用的功能系统如何进化，是一个真正的巨大挑战。本次研讨会将召集科学家，从遗传学家，生理学家，生态学家，到工程师，以促进鱼类体型的出现，作为一个模型系统，了解复杂的，相互作用的功能系统如何发展和进化。鱼的体形是一个复杂的形态，1）结果从许多，许多发展道路和2）功能在许多，许多不同的行为。从遗传学到工程学的新技术和新的理论模型整合了不同层次的生物组织（从基因到生态学），现在有可能了解从基因到体形、体形到功能、功能到动态环境中工作鱼体的许多途径的调节和协调。通过召集各种各样的研究人员，并鼓励与会者思考这些领域如何重叠和相互作用，本次研讨会将促进一个整体的，或系统的方法来理解复杂的功能系统。

PI: Jeffrey A. WalkerProposal Number: 0949102Proposal Title: Developmental and Evolutionary Regulation of Fish Body ShapeA major direction of current and future biological research is to understand how multiple, interacting functional systems coordinate to produce a body that works. This understanding is complicated by the fact that organisms need to work well in multiple environments, with both predictable and unpredictable environmental perturbations. Furthermore, organismal design reflects a history of past environments and not a plan for future environments. How complex, interacting functional systems evolve, then, is a truly grand challenge. This symposium will be held to convene scientists ranging from geneticists, to physiologists, to ecologists, to engineers to facilitate the emergence of fish body shape as a model system for understanding how complex, interacting functional systems develop and evolve. Fish body shape is a complex morphology that 1) results from many, many developmental paths and 2) functions in many, many different behaviors. Understanding the regulation and coordination of the many paths from genes to body shape, body shape to function, and function to a working fish body in a dynamic environment is now possible given new technologies from genetics to engineering and new theoretical models that integrate the different levels of biological organization (from genes to ecology). By convening a diverse array of researchers and encouraging participants to think about how these fields overlap and interact, this symposium will facilitate a holistic, or systems, approach to understanding complex functional systems.