Developmental and Evolutionary Regulation of Fish Body Shape, Conference Grant- the Society for Integrative and Comparative Biology annual meeting in Seattle WA, Jan. 4-7 2010

项目负责人：Jeffrey a . walker提案号：0949102提案标题：鱼类身体形状的发育和进化调控当前和未来生物学研究的主要方向是了解多个相互作用的功能系统如何协调产生一个有效的身体。生物体需要在多种环境中良好地工作，包括可预测的和不可预测的环境扰动，这一事实使这种理解变得复杂。此外，有机设计反映的是过去环境的历史，而不是对未来环境的规划。那么，复杂的、相互作用的功能系统如何进化，是一个真正的巨大挑战。本次研讨会将召集来自遗传学家、生理学家、生态学家和工程师的科学家，以促进鱼类身体形状的出现，作为理解复杂的、相互作用的功能系统如何发展和进化的模型系统。鱼的体型是一种复杂的形态，1)是许多许多发育途径的结果，2)是许多许多不同行为的功能。从遗传学到工程学的新技术，以及整合不同层次生物组织（从基因到生态学）的新理论模型，现在有可能理解从基因到身体形状、从身体形状到功能、从功能到动态环境中工作的鱼体的许多途径的调节和协调。通过召集各种各样的研究人员并鼓励参与者思考这些领域如何重叠和相互作用，本次研讨会将促进一个整体的或系统的方法来理解复杂的功能系统。

PI: Jeffrey A. WalkerProposal Number: 0949102Proposal Title: Developmental and Evolutionary Regulation of Fish Body ShapeA major direction of current and future biological research is to understand how multiple, interacting functional systems coordinate to produce a body that works. This understanding is complicated by the fact that organisms need to work well in multiple environments, with both predictable and unpredictable environmental perturbations. Furthermore, organismal design reflects a history of past environments and not a plan for future environments. How complex, interacting functional systems evolve, then, is a truly grand challenge. This symposium will be held to convene scientists ranging from geneticists, to physiologists, to ecologists, to engineers to facilitate the emergence of fish body shape as a model system for understanding how complex, interacting functional systems develop and evolve. Fish body shape is a complex morphology that 1) results from many, many developmental paths and 2) functions in many, many different behaviors. Understanding the regulation and coordination of the many paths from genes to body shape, body shape to function, and function to a working fish body in a dynamic environment is now possible given new technologies from genetics to engineering and new theoretical models that integrate the different levels of biological organization (from genes to ecology). By convening a diverse array of researchers and encouraging participants to think about how these fields overlap and interact, this symposium will facilitate a holistic, or systems, approach to understanding complex functional systems.